Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/47195
Título: | Portrait of gene expression in C. glabrata with stress induced by drugs |
Autor(es): | Rodrigues, Célia Fortuna Rodrigues, Maria Elisa Costa Henriques, Mariana |
Palavras-chave: | Candida glabrata Biofilms Matrices Genes Antifungal Resistance |
Data: | 22-Set-2017 |
Citação: | Rodrigues, Célia F.; Rodrigues, M. Elisa; Henriques, Mariana, Portrait of gene expression in C. glabrata with stress induced by drugs. Eurobiofilms 2017 - 5th European Congress on Microbial Biofilms. No. 134, Amesteram, Netherlands, 19-22 September, 204, 2017. |
Resumo(s): | Candidiasis have globally increased over the last years, being a major cause of morbidity and mortality, especially in immunosuppressed and hospitalized patients. Candida albicans remains to be the most common species responsible in candidiasis, but Candida glabrata has appeared as second most common Candida in the USA and the third in Europe. Biofilms of this species are extremely difficult to eradicate and are a source of many recalcitrant infections. The goal of this study was to evaluate how C. glabrata cells try to adjust their biofilm composition in response to an antifungal drug treatment based on a series of profiles of eight genes expression - BGL2, FKS1, FKS2, GAS2, KHN1, UPG1, XOG1 and MNN2 known to be related to the production of -1,3, -1,6-glucans and mannans. |
Tipo: | Resumo em ata de conferência |
Descrição: | Eurobiofilms 2017 - 5th European Congress on Microbial Biofilms |
URI: | https://hdl.handle.net/1822/47195 |
Versão da editora: | http://www.eurobiofilms.com/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_46977_1.pdf | Abstract | 404,54 kB | Adobe PDF | Ver/Abrir |
document_46977_2.pdf | Poster | 460,23 kB | Adobe PDF | Ver/Abrir |