Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/80985
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Ferreira, Patrícia | por |
dc.contributor.author | Lopes, Marlene | por |
dc.contributor.author | Belo, Isabel | por |
dc.date.accessioned | 2022-12-06T12:45:24Z | - |
dc.date.available | 2022-12-06T12:45:24Z | - |
dc.date.issued | 2022-11-30 | - |
dc.identifier.citation | Ferreira, P.; Lopes, M.; Belo, I. Use of Pressurized and Airlift Bioreactors for Citric Acid Production by Yarrowia lipolytica from Crude Glycerol. Fermentation 2022, 8, 700. https://doi.org/10.3390/fermentation8120700 | por |
dc.identifier.uri | https://hdl.handle.net/1822/80985 | - |
dc.description.abstract | Citric acid production is generally carried out in an aqueous medium in stirred tank reactors (STR), where the solubility of oxygen is low and the oxygen demand of microbial cultures is high. Thus, for this bioprocess, providing adequate oxygen mass transfer rate (OTR) from the gas phase into the aqueous culture medium is the main challenge of bioreactor selection and operation. In this study, citric acid production by Yarrowia lipolytica W29 from crude glycerol, in batch cultures, was performed in two non-conventional bioreactors normally associated with high mass transfer efficiency: a pressurized STR and an airlift bioreactor. Increased OTR was obtained by raising the total air pressure in the pressurized STR and by increasing the aeration rate in the airlift bioreactor. An improvement of 40% in maximum citric acid titer was obtained by raising the air pressure from 1 bar to 2 bar, whereas, in the airlift bioreactor, a 30% improvement was attained by increasing the aeration rate from 1 vvm to 1.5 vvm. Both bioreactor types can be successfully applied for the citric acid production process using alternative ways of improving OTR than increasing mechanical stirring power input, thus leading to important operating saving costs. | por |
dc.description.sponsorship | This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit; by LABBELS—Associate Laboratory in Biotechnology, Bioengineering and Microelectromechanical Systems, LA/P/0029/2020. | por |
dc.language.iso | eng | por |
dc.publisher | MDPI | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04469%2F2020/PT | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Yarrowia lipolytica | por |
dc.subject | Citric acid | por |
dc.subject | Crude glycerol | por |
dc.subject | Airlift bioreactor | por |
dc.subject | Pressurized bioreactor | por |
dc.subject | Oxygen mass transfer rate | por |
dc.title | Use of pressurized and airlift bioreactors for citric acid production by Yarrowia lipolytica from crude glycerol | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.mdpi.com/2311-5637/8/12/700 | por |
dc.comments | CEB55920 | por |
oaire.citationStartPage | 700 | por |
oaire.citationIssue | 12 | por |
oaire.citationVolume | 8 | por |
dc.date.updated | 2022-12-05T23:25:10Z | - |
dc.identifier.eissn | 2311-5637 | por |
dc.identifier.doi | 10.3390/fermentation8120700 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Fermentation | por |
oaire.version | VoR | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55920_1.pdf | 941,27 kB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons