Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/50090
Título: | Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies |
Autor(es): | Barrio, Irantzu Rodríguez-Álvarez, María Xosé Machado, Luís Meira Esteban, Cristobal Arostegui, Inmaculada |
Palavras-chave: | Categorisation Prediction models Cutpoint Cox model |
Data: | 2017 |
Editora: | Institut d'Estadística de Catalunya (Idescat) |
Revista: | SORT |
Resumo(s): | The Cox proportional hazards model is the most widely used survival prediction model for analysing time-to-event data. To measure the discrimination ability of a survival model the concordance probability index is widely used. In this work we studied and compared the performance of two different estimators of the concordance probability when a continuous predictor variable is categorised in a Cox proportional hazards regression model. In particular, we compared the c-index and the concordance probability estimator. We evaluated the empirical performance of both estimators through simulations. To categorise the predictor variable we propose a methodology which considers the maximal discrimination attained for the categorical variable. We applied this methodology to a cohort of patients with chronic obstructive pulmonary disease, in particular, we categorised the predictor variable forced expiratory volume in one second in percentage. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/50090 |
DOI: | 10.2436/20.8080.02.51 |
ISSN: | 1696-2281 |
e-ISSN: | 2013-8830 |
Versão da editora: | http://www.raco.cat/index.php/SORT/article/view/326049 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CMAT - Artigos em revistas com arbitragem / Papers in peer review journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2017 SORT.pdf Acesso restrito! | 288,83 kB | Adobe PDF | Ver/Abrir |