Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/50090
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Campo DC | Valor | Idioma |
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dc.contributor.author | Barrio, Irantzu | por |
dc.contributor.author | Rodríguez-Álvarez, María Xosé | por |
dc.contributor.author | Machado, Luís Meira | por |
dc.contributor.author | Esteban, Cristobal | por |
dc.contributor.author | Arostegui, Inmaculada | por |
dc.date.accessioned | 2018-02-06T09:04:08Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1696-2281 | por |
dc.identifier.uri | https://hdl.handle.net/1822/50090 | - |
dc.description.abstract | The Cox proportional hazards model is the most widely used survival prediction model for analysing time-to-event data. To measure the discrimination ability of a survival model the concordance probability index is widely used. In this work we studied and compared the performance of two different estimators of the concordance probability when a continuous predictor variable is categorised in a Cox proportional hazards regression model. In particular, we compared the c-index and the concordance probability estimator. We evaluated the empirical performance of both estimators through simulations. To categorise the predictor variable we propose a methodology which considers the maximal discrimination attained for the categorical variable. We applied this methodology to a cohort of patients with chronic obstructive pulmonary disease, in particular, we categorised the predictor variable forced expiratory volume in one second in percentage. | por |
dc.description.sponsorship | This study was supported by grants IT620-13 from the Departamento de Educacion, Politica Linguistica y Cultura del Gobierno Vasco, MTM2013-40941-P, MTM2014-55966-P and MTM2016-74931-P from the Ministerio de Economia y Competitividad and FEDER and the Agrupamento INBIOMED from DXPCTSUG-FEDER unha maneira de facer Europa (2012/273). Maria Xose Rodriguez-Alvarez acknowledges financial support for Severo Ochoa Program SEV-2013-0323 and Basque Government BERC Program 2014-2017. Luis Meira-Machado acknowledges financial support for Portuguese Funds through FCT-"Fundacao para a Ciencia e a Tecnologia", within Project UID/MAT/00013/2013. The collection of the COPD data used for this study was supported in part by grants PI020510 from the Fondo de Investigacion Sanitaria and 200111002, 2005111008, from the Departamento de Salud del Gobierno Vasco and the Research Committee Hospital Galdakao-Usansolo. | por |
dc.language.iso | eng | por |
dc.publisher | Institut d'Estadística de Catalunya (Idescat) | por |
dc.rights | restrictedAccess | por |
dc.subject | Categorisation | por |
dc.subject | Prediction models | por |
dc.subject | Cutpoint | por |
dc.subject | Cox model | por |
dc.title | Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.raco.cat/index.php/SORT/article/view/326049 | por |
oaire.citationStartPage | 73 | por |
oaire.citationEndPage | 92 | por |
oaire.citationIssue | 1 | por |
oaire.citationVolume | 41 | por |
dc.identifier.eissn | 2013-8830 | por |
dc.identifier.doi | 10.2436/20.8080.02.51 | por |
dc.subject.fos | Ciências Naturais::Matemáticas | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | SORT | por |
Aparece nas coleções: | CMAT - Artigos em revistas com arbitragem / Papers in peer review journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2017 SORT.pdf Acesso restrito! | 288,83 kB | Adobe PDF | Ver/Abrir |