Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/49070
Título: | New 2,4,5-triarylimidazoles based on a phenylalanine core: synthesis, photophysical characterization and evaluation as fluorimetric chemosensors for ion recognition |
Autor(es): | Esteves, Cátia Isabel Canavezes Raposo, M. Manuela M. Costa, Susana P. G. |
Palavras-chave: | 2,4,5-triarylimidazoles Phenylalanine Unnatural amino acids Chemosensors Fluorescence |
Data: | Jul-2016 |
Editora: | Elsevier 1 |
Revista: | Dyes and Pigments |
Citação: | Dyes and Pigments, 2016, 134, 258-268 |
Resumo(s): | Novel fluorescent 4,5-diarylimidazolyl-phenylalanines 3a-d were prepared by reaction of N-tert-butyloxycarbonyl-4-formylphenylalanine methyl ester and appropriate (hetero)aromatic diones. The photophysical properties of these new unnatural amino acids were evaluated by UV-Vis absorption and fluorescence spectroscopy in solvents of different character and aqueous mixtures with acetonitrile. They were evaluated as novel amino acid based fluorimetric chemosensors for ions through spectrophotometric and spectrofluorimetric titrations with biologically and analytically important anions and cations such as F-, OH-, Cu2+ and Fe3+. The results indicate that there was a strong interaction through the donor N, O and S atoms at the side chain, especially for 4,5-di(furan-2’-yl)imidazolyl-phenylalanine 3a and 4,5-di(thiophen-2’-yl)imidazolyl-phenylalanine 3b with Cu2+ and Fe3+, in a 1:1 complex stoichiometry. The photophysical and metal ion sensing properties of these amino acids suggest that they can be suitable for incorporation into chemosensory peptidic frameworks. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/49070 |
DOI: | 10.1016/j.dyepig.2016.07.020 |
ISSN: | 0143-7208 |
e-ISSN: | 1873-3743 |
Versão da editora: | https://doi.org/10.1016/j.dyepig.2016.07.020 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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artigo Esteves DYPI 2016.pdf | 1,96 MB | Adobe PDF | Ver/Abrir |