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https://hdl.handle.net/1822/46936
Título: | Morphological transition of Helicobacter pylori adapted to water |
Autor(es): | Fernandes, R. Silva, H. Oliveira, Ricardo Almeida, Carina Azevedo, N. F. Vieira, Maria João |
Palavras-chave: | Helicobacter pylori Adaptation Morphological transition Peptidoglycan Water |
Data: | 7-Set-2017 |
Editora: | Future Medicine Ltd |
Revista: | Future Microbiology |
Citação: | Fernandes, R.; Silva, H.; Oliveira, R.; Almeida, Carina; Azevedo, N. F.; Vieira, Maria João, Morphological transition of Helicobacter pylori adapted to water. Future Microbiology, 12(13), 1167-1179, 2017 |
Resumo(s): | Aim: This study aims to investigate the morphological transition of Helicobacter pylori during adaptation to water. Materials \& methods: Different strains were adapted to water. Changes regarding cultivability and cellular morphology were recorded. Expression of 11 genes involved in H. pylori morphological changes was evaluated by real-time PCR. Results: H. pylori presented increased cultivability in water after adaptation. The permanent loss of the spiral shape was observed, but no transition into coccoid form has occurred. Expression levels of genes involved in peptidoglycan assembly of H. pylori 26695 have shown significant changes between adapted and nonadapted strains. Conclusion: Adaption to water favors the culturable phenotype and the morphological transition to the rod shape, into a process that implicates the peptidoglycan turnover. |
Tipo: | Artigo |
Descrição: | To view the supplementary data that accompany this paper please visit the journal website at: www. futuremedicine.com /doi/full/10.2217/fmb-2016-0174. |
URI: | https://hdl.handle.net/1822/46936 |
DOI: | 10.2217/fmb-2016-0174 |
ISSN: | 1746-0913 |
e-ISSN: | 1746-0921 |
Versão da editora: | http://www.futuremedicine.com/loi/fmb |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_47063_1.pdf | 3,95 MB | Adobe PDF | Ver/Abrir |