Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/46936
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Fernandes, R. | por |
dc.contributor.author | Silva, H. | por |
dc.contributor.author | Oliveira, Ricardo | por |
dc.contributor.author | Almeida, Carina | por |
dc.contributor.author | Azevedo, N. F. | por |
dc.contributor.author | Vieira, Maria João | por |
dc.date.accessioned | 2017-10-31T15:29:35Z | - |
dc.date.available | 2017-10-31T15:29:35Z | - |
dc.date.issued | 2017-09-07 | - |
dc.identifier.citation | Fernandes, R.; Silva, H.; Oliveira, R.; Almeida, Carina; Azevedo, N. F.; Vieira, Maria João, Morphological transition of Helicobacter pylori adapted to water. Future Microbiology, 12(13), 1167-1179, 2017 | por |
dc.identifier.issn | 1746-0913 | por |
dc.identifier.uri | https://hdl.handle.net/1822/46936 | - |
dc.description | To view the supplementary data that accompany this paper please visit the journal website at: www. futuremedicine.com /doi/full/10.2217/fmb-2016-0174. | por |
dc.description.abstract | Aim: This study aims to investigate the morphological transition of Helicobacter pylori during adaptation to water. Materials \& methods: Different strains were adapted to water. Changes regarding cultivability and cellular morphology were recorded. Expression of 11 genes involved in H. pylori morphological changes was evaluated by real-time PCR. Results: H. pylori presented increased cultivability in water after adaptation. The permanent loss of the spiral shape was observed, but no transition into coccoid form has occurred. Expression levels of genes involved in peptidoglycan assembly of H. pylori 26695 have shown significant changes between adapted and nonadapted strains. Conclusion: Adaption to water favors the culturable phenotype and the morphological transition to the rod shape, into a process that implicates the peptidoglycan turnover. | por |
dc.description.sponsorship | This work was supported by the Portuguese Foundation for Science and Technology (FCT) under the project ‘Heliwater’ (PTDC/BIA-MIC/108811/2008), the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 – Programa Operacional Regional do Norte. No writing assistance was utilized in the production of this manuscript. | por |
dc.language.iso | eng | por |
dc.publisher | Future Medicine Ltd | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/108811/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147337/PT | por |
dc.rights | openAccess | por |
dc.subject | Helicobacter pylori | por |
dc.subject | Adaptation | por |
dc.subject | Morphological transition | por |
dc.subject | Peptidoglycan | por |
dc.subject | Water | por |
dc.title | Morphological transition of Helicobacter pylori adapted to water | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.futuremedicine.com/loi/fmb | por |
dc.comments | CEB47063 | por |
oaire.citationStartPage | 1167 | por |
oaire.citationEndPage | 1179 | por |
oaire.citationIssue | 13 | por |
oaire.citationConferencePlace | United Kingdom | - |
oaire.citationVolume | 12 | por |
dc.date.updated | 2017-10-29T18:22:59Z | - |
dc.identifier.eissn | 1746-0921 | por |
dc.identifier.doi | 10.2217/fmb-2016-0174 | por |
dc.identifier.pmid | 28879777 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Future Microbiology | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_47063_1.pdf | 3,95 MB | Adobe PDF | Ver/Abrir |