Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/46390

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dc.contributor.authorSá, M.por
dc.contributor.authorAzóia, Nuno G.por
dc.contributor.authorMelle-Franco, Manuelpor
dc.contributor.authorRibeiro, Arturpor
dc.contributor.authorCavaco-Paulo, Arturpor
dc.date.accessioned2017-09-11T10:54:57Z-
dc.date.available2017-09-11T10:54:57Z-
dc.date.issued2017-07-
dc.identifier.citationSá, M.; Azoia, Nuno G.; Melle-Franco, Manuel; Ribeiro, Artur; Cavaco-Paulo, Artur, Permeation of skin with (C60) fullerene dispersions. Engineering in Life Sciences, 17(7), 732-738, 2017por
dc.identifier.issn1618-0240por
dc.identifier.urihttps://hdl.handle.net/1822/46390-
dc.description.abstractDispersions in transcutol/isopropyl myristate make C60 fullerene molecules suitable for transdermal delivery. We found that C60 can successfully permeate the skin using pig skin in Franz diffusion cells. Molecular dynamics simulations and transmission electron microscopy confirmed these observations. Basic cosmetic formulations with transcutol/ isopropyl myristate without harsh organic solvents show a high potential for delivery of C60 for biopharmaceutical and cosmetics applications.por
dc.description.sponsorshipThis study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI01-0145-FEDER-006684).). Artur Ribeiro thanks FCT for the SFRH\BPD\98388\2013 grant.por
dc.language.isoengpor
dc.publisherWiley-Blackwellpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147337/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F98388%2F2013/PTpor
dc.rightsopenAccesspor
dc.subjectDeliverypor
dc.subjectDispersionpor
dc.subjectFullerene C60por
dc.subjectTransdermalpor
dc.subjectCosmeticspor
dc.titlePermeation of skin with (C60) fullerene dispersionspor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1618-2863por
dc.commentsCEB46635por
oaire.citationStartPage732por
oaire.citationEndPage738por
oaire.citationIssue7por
oaire.citationConferencePlaceUnited Kingdom-
oaire.citationVolume17por
dc.date.updated2017-08-03T11:01:25Z-
dc.identifier.eissn1618-2863por
dc.identifier.doi10.1002/elsc.201600244por
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersionpor
dc.subject.wosScience & Technologypor
sdum.journalEngineering in Life Sciencespor
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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