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https://hdl.handle.net/1822/32115
Título: | Antifungal activity of phenolic compounds identified in flowers from the North Eastern Portugal against Candida species |
Autor(es): | Alves, Carlos Ferreira, Isabel C. F. R. Barros, Lillian Silva, Sónia Carina Azeredo, Joana Henriques, Mariana |
Palavras-chave: | antifungal effect biofilms Candida species medicinal flowers phenolic compounds |
Data: | 2014 |
Editora: | Future Medicine |
Revista: | Future Microbiology |
Citação: | Alves, Carlos; Ferreira, Isabel; Barros, Lillian; Silva, Sónia Carina; Azeredo, Joana; Henriques, Mariana, Antifungal activity of phenolic compounds identified in flowers from the North Eastern Portugal against Candida species. Future Microbiology, 9(2), 139-146, 2014 |
Resumo(s): | Aim: To evaluate the antifungal effect of gallic acid, catechin, luteolin and quercetin, phenolic compounds identified from flowers of the North Eastern Portugal, against Candida planktonic and biofilm cells. Materials and Methods: The minimal inhibitory concentrations (MIC) were determined in Candida planktonic cells and the effect of phenolic compounds on Candida biofilms was assessed through quantification by colony forming units (CFUs). Results: MIC values demonstrated that gallic acid presented the highest effect against the all Candida species. Catechin showed a similar effect against C. albicans ATCC 90028cells. Additionally, gallic acid and quercetin had demonstrated only a minimum effect against Candida species biofilms. Conclusions: Gallic acid affected the growth of the different planktonic Candida species in all concentrations used, still catechin showed a similar effect against C. albicans ATCC 90028and C. glabrata ATCC 2001cells.Additionally, only gallic acid and quercetin demonstrated a slight effect against all Candida species biofilms. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/32115 |
DOI: | 10.2217/FMB.13.147 |
ISSN: | 1746-0913 |
e-ISSN: | 1746-0921 |
Versão da editora: | www.ncbi.nlm.nih.gov/pubmed/24571069 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_15716_1.pdf | 1,25 MB | Adobe PDF | Ver/Abrir |