Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/91100
Título: | Bioinformatic tools for exploring the SUMO gene network: An update |
Autor(es): | Castro, Pedro Humberto Santos, Miguel Ângelo Magalhães, Alexandre Papadopoulos Tavares, R. M. Azevedo, Herlander |
Palavras-chave: | Arabidopsis Bioinformatics Data mining Functional categorization Gene expression Gene network Posttranslational modification Small ubiquitin-related modifier (SUMO) |
Data: | 2023 |
Revista: | Methods in Molecular Biology |
Resumo(s): | Plant sumoylation research has seen significant advances in recent years, particularly since high-throughput proteomic strategies have enabled the discovery of more than one thousand SUMO targets. In the present chapter, we update the previously reported SUMO (small ubiquitin-related modifier) gene network (SGN) to its v4 iteration. SGN is a curated assembly of Arabidopsis thaliana genes that have been functionally associated with sumoylation, from SUMO pathway components to targets and interactors. The enclosed tutorial helps interpret and manage these datasets and details bioinformatic tools that can be used for in silico-based hypothesis generation. The latter include tools for sumoylation site prediction, comparative genomics, and gene network analysis. |
Tipo: | Capítulo de livro |
URI: | https://hdl.handle.net/1822/91100 |
DOI: | 10.1007/978-1-0716-2784-6_26 |
ISSN: | 1064-3745 36413331 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CBFP - Livros e Capítulos de Livros/Books and Books Chapters |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Chapter - Castro PH et al. (2022) Bioinformatics tools for exploring the SUMO Gene Network, an update.pdf Acesso restrito! | 2,29 MB | Adobe PDF | Ver/Abrir |