Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/88446
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Öztuerk-Öncel, M. Ö. | por |
dc.contributor.author | Leal-Martínez, Baltazar Hiram | por |
dc.contributor.author | Monteiro, Rosa F. | por |
dc.contributor.author | Gomes, Manuela E. | por |
dc.contributor.author | Domingues, Rui Miguel Andrade | por |
dc.date.accessioned | 2024-02-02T09:34:37Z | - |
dc.date.available | 2024-02-02T09:34:37Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.citation | Öztuerk-Öncel M. Ö., Leal-Martínez B. H., Monteiro R. F., Gomes M. E., Domingues R. M. A. A dive into the bath: embedded 3D bioprinting of freeform in vitro models, Biomaterials Science, Vol. 11, pp. 5462-5473, doi:10.1039/D3BM00626C, 2023 | por |
dc.identifier.issn | 2047-4849 | por |
dc.identifier.uri | https://hdl.handle.net/1822/88446 | - |
dc.description.abstract | Designing functional, vascularized, human scale in vitro models with biomimetic architectures and multiple cell types is a highly promising strategy for both a better understanding of natural tissue/organ development stages to inspire regenerative medicine, and to test novel therapeutics on personalized microphysiological systems. Extrusion-based 3D bioprinting is an effective biofabrication technology to engineer living constructs with predefined geometries and cell patterns. However, bioprinting high-resolution multilayered structures with mechanically weak hydrogel bioinks is challenging. The advent of embedded 3D bioprinting systems in recent years offered new avenues to explore this technology for in vitro modeling. By providing a stable, cell-friendly and perfusable environment to hold the bioink during and after printing, it allows to recapitulate native tissues’ architecture and function in a well-controlled manner. Besides enabling freeform bioprinting of constructs with complex spatial organization, support baths can further provide functional housing systems for their long-term in vitro maintenance and screening. This minireview summarizes the recent advances in this field and discuss the enormous potential of embedded 3D bioprinting technologies as alternatives for the automated fabrication of more biomimetic in vitro models. | por |
dc.description.sponsorship | The authors acknowledge the financial support from Project NORTE-01-0145-FEDER 000021 supported by Norte Portugal Regional Operational Program (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), the European Union Framework Program for Research and Innovation HORIZON 2020, under European Research Council Grant Agreement 772817 and 101069302, Fundação para a Ciência e a Tecnologia (FCT) for the for Contract 2020.03410.CEECIND (to R. M. A. D.) and Wi-Pi project 2022.05526.PTDC. The schematics of the Table of Contents graphic was created with BioRender.com. | por |
dc.language.iso | eng | por |
dc.publisher | Royal Society of Chemistry | por |
dc.relation | NORTE-01-0145-FEDER 000021 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/CEEC IND 3ed/2020.03410.CEECIND%2FCP1600%2FCT0013/PT | por |
dc.relation | 2022.05526.PTDC | por |
dc.rights | openAccess | por |
dc.subject | 3D bioprinting | por |
dc.subject | In vitro 3d models | por |
dc.subject | Support bath | por |
dc.title | A dive into the bath: embedded 3D bioprinting of freeform in vitro models | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://doi.org/10.1039/D3BM00626C | por |
dc.comments | http://3bs.uminho.pt/node/21025 | por |
oaire.citationStartPage | 5462 | por |
oaire.citationEndPage | 5473 | por |
oaire.citationIssue | 16 | por |
oaire.citationVolume | 11 | por |
dc.date.updated | 2024-02-01T16:12:20Z | - |
dc.identifier.doi | 10.1039/D3BM00626C | por |
dc.identifier.pmid | 37489648 | por |
sdum.journal | Biomaterials Science | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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21025-rsc-minireview-13042023-final.pdf | 1,36 MB | Adobe PDF | Ver/Abrir |