Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/87327
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Esteves, Cátia I. C. | por |
dc.contributor.author | Raposo, M. Manuela M. | por |
dc.contributor.author | Costa, Susana P. G. | por |
dc.date.accessioned | 2023-11-27T08:21:44Z | - |
dc.date.available | 2023-11-27T08:21:44Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Esteves, C. I. C.; Raposo, M. M. M.; Costa, S. P. G. New amino acid-based thiosemicarbazones and hydrazones: synthesis and evaluation as fluorimetric chemosensors in aqueous mixtures. Molecules 2023, 28(21), 7256. | por |
dc.identifier.issn | 1420-3049 | por |
dc.identifier.uri | https://hdl.handle.net/1822/87327 | - |
dc.description.abstract | A series of new phenylalanine derivatives bearing thiosemicarbazone and hydrazone units at the side chain were synthesised and evaluated as fluorimetric chemosensors for ions. They were tested for the recognition of organic and inorganic anions, (such as AcO-, F-, Cl-, Br-, I-, ClO4-, CN-, NO3-, BzO-, OH-, H2PO4- and HSO4-) and of alkaline, alkaline-earth, and transition metal cations, (such as Na+, K+, Cs+, Ag+, Cu+, Cu2+, Ca2+, Cd2+, Co2+, Pb2+, Pd2+, Ni2+, Hg2+, Zn2+, Fe2+, Fe3+ and Cr3+) in acetonitrile and its aqueous mixtures in varying ratio through spectrofluorimetric titrations. The results indicate that there is a strong interaction through the donor N, O and S atoms at the side chain of the various phenylalanines, with higher sensitivity for Cu2+, Fe3+ and F- in a 1:2 ligand-ion stoichiometry. The photophysical and metal ion sensing properties of these phenylalanines suggest that they can be suitable for incorporation into peptidic chemosensory frameworks. | por |
dc.description.sponsorship | This research was funded by the Foundation for Science and Technology (FCT) for financial support to CQ-UM [PEst-C/QUI/UI0686/2013 (FCOMP-01-0124-FEDER-037302)], CQUM (UIDB/00686/2020) and a PhD grant to C.I.C. Esteves (SFRH/BD/68360/2010). The NMR spectrometer Bruker Avance III 400 is part of the National NMR Network and was purchased within the framework of the National Program for Scientific Re-equipment with funds from POCI 2010 (FEDER) and FCT | por |
dc.language.iso | eng | por |
dc.publisher | MDPI | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FQUI%2FUI0686%2F2013/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00686%2F2020/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/FARH/SFRH%2FBD%2F68360%2F2010/PT | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Hydrazone | por |
dc.subject | Thiosemicarbazone | por |
dc.subject | Phenylalanine | por |
dc.subject | Unnatural amino acids | por |
dc.subject | Fluorescence | por |
dc.subject | Chemosensors | por |
dc.subject | Synthesis | por |
dc.subject | Heterocycles | por |
dc.title | New amino acid-based thiosemicarbazones and hydrazones: synthesis and evaluation as fluorimetric chemosensors in aqueous mixtures | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://doi.org/10.3390/molecules28217256 | por |
oaire.citationStartPage | 7256 | por |
oaire.citationIssue | 21 | por |
oaire.citationVolume | 28 | por |
dc.identifier.doi | 10.3390/molecules28217256 | por |
dc.identifier.pmid | 37959675 | por |
dc.subject.fos | Ciências Naturais::Ciências Químicas | por |
sdum.journal | Molecules | por |
oaire.version | VoR | por |
dc.subject.ods | Saúde de qualidade | por |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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molecules-28-07256-v2.pdf | manuscript | 2,15 MB | Adobe PDF | Ver/Abrir |
molecules-2535695-supplementary.pdf | Supporting information | 2,66 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons