Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/86986
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Ferreira, Joana | por |
dc.contributor.author | Afonso, Julieta Alexandra Pereira | por |
dc.contributor.author | Carneiro, Alexandre Lima | por |
dc.contributor.author | Vila, Isabel | por |
dc.contributor.author | Cunha, Cristina | por |
dc.contributor.author | Roque, Susana | por |
dc.contributor.author | Silva, Cristina | por |
dc.contributor.author | Mesquita, Amílcar | por |
dc.contributor.author | Cotter, Jorge | por |
dc.contributor.author | Correia-Neves, M | por |
dc.contributor.author | Mansilha, Armando | por |
dc.contributor.author | Longatto, Adhemar | por |
dc.contributor.author | Cunha, Pedro | por |
dc.date.accessioned | 2023-10-19T09:12:26Z | - |
dc.date.available | 2023-10-19T09:12:26Z | - |
dc.date.issued | 2023-06-25 | - |
dc.identifier.citation | Ferreira, J.; Afonso, J.; Carneiro, A.L.; Vila, I.; Cunha, C.; Roque, S.; Silva, C.; Mesquita, A.; Cotter, J.; Correia-Neves, M.; et al. Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population. J. Cardiovasc. Dev. Dis. 2023, 10, 271. https://doi.org/10.3390/jcdd10070271 | por |
dc.identifier.uri | https://hdl.handle.net/1822/86986 | - |
dc.description.abstract | The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors, anthropometric measures and medication. An observational and prospective study was conducted, and 177 subjects were included. Peri-aortic adipose tissue had the highest density, while the subcutaneous adipose tissue had the lowest. The density of subcutaneous adipose tissue differs from the density of visceral (p = 0.00) and peri-aortic adipose tissue (p = 0.00). Smokers/ex-smokers had a lower area (p = 0.00) and density (p = 0.02) of subcutaneous adipose tissue. Multiple linear regression analysis showed that sex was a predictor of subcutaneous adipose tissue area (β = −0.27, t = −3.12, p = 0.00) but smoking habits were not. After controlling for sex, we found that the association between smokers/ex-smokers and area of subcutaneous adipose tissue was lost, but the association with density persisted. Patients with hypertension had a higher visceral adipose tissue area, and this relationship was maintained even after adjusting for gender. Peri-aortic adipose tissue is similar to visceral and distinct from subcutaneous adipose tissue. Cardiovascular risk factors have different influences in distinct adipose compartments. | por |
dc.description.sponsorship | This work was developed under the scope of project NORTE-01-0145-FEDER- 000013, supported by the Northern Portugal Regional Operational Programme (NORTE 2020) under the Portugal Partnership Agreement, through the European Regional Development Fund (FEDER), and by national funds, through the Foundation for Science and Technology (FCT)—project UIDB/50026/2020 and UIDP/50026/2020. J.A. received a fellowship from Foundation for Science and Technology (FCT), reference SFRH/BPD/116784/2016. | por |
dc.language.iso | eng | por |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | por |
dc.relation | NORTE-01-0145-FEDER-000013 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50026%2F2020/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50026%2F2020/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBPD%2F116784%2F2016/PT | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Adipose tissue | por |
dc.subject | Inflammation | por |
dc.subject | Cardiovascular risk factors | por |
dc.subject | Statins | por |
dc.subject | Angiotensin-converting-enzyme inhibitors | por |
dc.subject | Angiotensin receptor antagonist | por |
dc.title | Exploring the diversity of visceral, subcutaneous and perivascular adipose tissue in a vascular surgery population | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.mdpi.com/2308-3425/10/7/271 | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 17 | por |
oaire.citationIssue | 7 | por |
oaire.citationVolume | 10 | por |
dc.date.updated | 2023-07-28T12:21:35Z | - |
dc.identifier.eissn | 2308-3425 | - |
dc.identifier.doi | 10.3390/jcdd10070271 | por |
sdum.journal | Journal of Cardiovascular Development and Disease | por |
oaire.version | VoR | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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jcdd-10-00271-v2.pdf | 855,93 kB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons