Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/86956
Título: | The hurdles of collagen shrinkage: a promising GelMA-based organotypic skin approach |
Autor(es): | Eltayari, Zahara Saoud Faria Gasperini, Luca Marques, A. P. |
Palavras-chave: | bioreactor organotypic skin |
Data: | Jun-2023 |
Editora: | Mary Ann Liebert |
Revista: | Tissue Engineering. Part A |
Citação: | Eltayari Z., Gasperini L., Marques A. P. The hurdles of Collagen shrinkage: A promising GelMA-based organotypic skin approach, Tissue Engineering: Part A, Vol. 29, Issue 13-14, pp. 53, doi:0.1089/ten.tea.2023.29043.abstracts, 2023 |
Resumo(s): | [Excerpt] Introduction: Collagen I (Col I) is the gold standard material to generate many in vitro tissue models, including organotypic skin. Col I remodeling by fibroblasts incorporated in the dermal part of the model leads to significant dimensional changes associated with additional hurdles when cultured within dynamic culture systems. These systems are relevant for the biofunctionality mimicry of the skin due to its multilayered nature and by providing the necessary fluid flow conditioning. Gelatin methacrylate (GelMA) is proposed in this study to validate a dimensionally stable organotypic skin model developed and maintained in a custom-made bioreactor [1], generating a dynamic in vitro testing platform. [...] |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/86956 |
ISSN: | 1937-3341 |
Versão da editora: | https://doi.org/10.1089/ten.tea.2023.29043.abstracts |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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20995-abstract-termis-2023.pdf | 601,75 kB | Adobe PDF | Ver/Abrir |