Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/80791
Título: | Oxidative precipitation synthesis of calcium-doped manganese ferrite nanoparticles for magnetic hyperthermia |
Autor(es): | Veloso, Sérgio Rafael Silva Andrade, Raquel G. D. Gomes, Valéria Amorim, Carlos O. Amaral, Vítor S. Salgueiriño, Verónica Coutinho, Paulo J. G. Ferreira, Paula M. T. Correa-Duarte, Miguel A. Castanheira, Elisabete M. S. |
Palavras-chave: | Magnetic nanoparticles Superparamagnetism Citrate-stabilization Calcium ferrites Manganese ferrites Magnetic hyperthermia |
Data: | 16-Nov-2022 |
Editora: | Multidisciplinary Digital Publishing Institute (MDPI) |
Revista: | International Journal of Molecular Sciences |
Citação: | Veloso, S.R.S.; Andrade, R.G.D.; Gomes, V.; Amorim, C.O.; Amaral, V.S.; Salgueiriño, V.; Coutinho, P.J.G.; Ferreira, P.M.T.; Correa-Duarte, M.A.; Castanheira, E.M.S. Oxidative Precipitation Synthesis of Calcium-Doped Manganese Ferrite Nanoparticles for Magnetic Hyperthermia. Int. J. Mol. Sci. 2022, 23, 14145. https://doi.org/10.3390/ijms232214145 |
Resumo(s): | Superparamagnetic nanoparticles are of high interest for therapeutic applications. In this work, nanoparticles of calcium-doped manganese ferrites (CaxMn1−xFe2O4) functionalized with citrate were synthesized through thermally assisted oxidative precipitation in aqueous media. The method provided well dispersed aqueous suspensions of nanoparticles through a one-pot synthesis, in which the temperature and Ca/Mn ratio were found to influence the particles microstructure and morphology. Consequently, changes were obtained in the optical and magnetic properties that were studied through UV-Vis absorption and SQUID, respectively. XRD and Raman spectroscopy studies were carried out to assess the microstructural changes associated with stoichiometry of the particles, and the stability in physiological pH was studied through DLS. The nanoparticles displayed high values of magnetization and heating efficiency for several alternating magnetic field conditions, compatible with biological applications. Hereby, the employed method provides a promising strategy for the development of particles with adequate properties for magnetic hyperthermia applications, such as drug delivery and cancer therapy. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/80791 |
DOI: | 10.3390/ijms232214145 |
ISSN: | 1661-6596 |
e-ISSN: | 1422-0067 |
Versão da editora: | https://www.mdpi.com/1422-0067/23/22/14145 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | PHYSICS OF QUANTUM MATERIALS AND BIONANOSTRUCTURES (2018 - ...) CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
ijms-23-14145.pdf | Main article | 4,79 MB | Adobe PDF | Ver/Abrir |
ijms-2020205-supplementary.pdf | Supplementary Material | 2,38 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons