Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/76405

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dc.contributor.authorMiranda, Catarina S.por
dc.contributor.authorAntunes, Joana Isabel Costapor
dc.contributor.authorHomem, Natália Cândidopor
dc.contributor.authorFelgueiras, Helena Pradopor
dc.date.accessioned2022-03-04T09:52:43Z-
dc.date.available2022-03-04T09:52:43Z-
dc.date.issued2021-
dc.identifier.urihttps://hdl.handle.net/1822/76405-
dc.description.abstract[Excerpt] Pseudomonas aeruginosa is considered a public threat, with a great number of antibiotic resistant microorganisms. Essential oils (EOs) have demonstrated significant effects against several pathogens, however, they present a volatile nature, therefore, biodegradable polymeric delivery platforms are being engineered. Here, hydrogel-like films were produced from a combination of sodium alginate (SA) and gelatin (GN) to serve as delivery platforms for the controlled release of cinnamon leaf oil (CLO) entrapped within chitosan (CS) microcapsules. CS microcapsules were prepared via ionotropic gelation with tripolyphosphate (TPP), with CLO at minimum inhibitory concentration (MIC) in the core. Microcapsules were then embedded within a biodegradable SA/GN polymeric matrix processed via a solvent casting/phase inversion methodology with SA/GN used at 70/30 polymer ratio and 2 wt% SA concentration in distilled water. The coagulation bath was composed of a 2 wt% calcium chloride (CaCl2 ) aqueous solution. Qualitative and quantitative antimicrobial examinations validated the modified film potential to fight infections caused by P. aeruginosa bacteria.por
dc.language.isoengpor
dc.publisherMDPIpor
dc.relationPOCI-01-0145-FEDER-028074por
dc.relationUID/CTM/00264/2021por
dc.rightsopenAccesspor
dc.titleFighting Pseudomonas aeruginosa-prevalent wound infections by means of natural-origin compoundspor
dc.typeconferencePosterpor
dc.peerreviewedyespor
sdum.event.titleThe 1st International Electronic Conference on Clinical Medicine (ECCM 2021)por
sdum.event.typeconferencepor
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