Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/75320
Título: | Lipid nanoparticles for the posterior eye segment |
Autor(es): | Bonilla, Lorena Espina, Marta Severino, Patricia Cano, Amanda Ettcheto, Miren Camins, Antoni García, Maria Luisa Souto, Eliana B. Sánchez-López, Elena |
Palavras-chave: | Ocular drug delivery Ocular barriers Lipid nanoparticles Posterior segment Drug transport NLC SLN |
Data: | 2022 |
Editora: | Multidisciplinary Digital Publishing Institute (MDPI) |
Revista: | Pharmaceutics |
Citação: | Bonilla, Lorena; Espina, Marta; Severino, Patricia; Cano, Amanda; Ettcheto, Miren; Camins, Antoni; García, Maria Luisa; Souto, Eliana B.; Sánchez-López, Elena, Lipid nanoparticles for the posterior eye segment. Pharmaceutics, 14(1), 90, 2022 |
Resumo(s): | This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most relevant diseases affecting the posterior segment will be summarized. Moreover, preparation methods and different types and subtypes of lipid nanoparticles will also be reviewed. Lipid nanoparticles used as carriers to deliver drugs to the posterior eye segment as well as their administration routes, pharmaceutical forms and ocular distribution will be discussed emphasizing the different targeting strategies most recently employed for ocular drug delivery. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/75320 |
DOI: | 10.3390/pharmaceutics14010090 |
ISSN: | 1999-4923 |
Versão da editora: | https://www.mdpi.com/1999-4923/14/1/90 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55122_1.pdf | 3,23 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons