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https://hdl.handle.net/1822/74303
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Campo DC | Valor | Idioma |
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dc.contributor.author | Fernandes, Tiago A. | por |
dc.contributor.author | Costa, Inês F. M. | por |
dc.contributor.author | Jorge, Paula Alexandra Silva | por |
dc.contributor.author | Sousa, Ana Catarina | por |
dc.contributor.author | André, Vânia | por |
dc.contributor.author | Cerca, Nuno | por |
dc.contributor.author | Kirillov, Alexander M. | por |
dc.date.accessioned | 2021-10-11T10:51:53Z | - |
dc.date.issued | 2021-03-11 | - |
dc.identifier.citation | Fernandes, Tiago A.; Costa, Inês F. M.; Jorge, Paula; Sousa, Ana Catarina; André, Vânia; Cerca, Nuno; Kirillov, Alexander M., Silver(I) coordination polymers immobilized into biopolymer films for antimicrobial applications. ACS Applied Materials & Interfaces, 13(11), 12836-12844, 2021 | por |
dc.identifier.issn | 1944-8244 | por |
dc.identifier.uri | https://hdl.handle.net/1822/74303 | - |
dc.description.abstract | This study describes a template-mediated self-assembly synthesis, full characterization, and structural features of two new silver-based bioactive coordination polymers (CPs) and their immobilization into acrylated epoxidized soybean oil (ESOA) biopolymer films for antimicrobial applications. The 3D silver(I) CPs [Ag4(?8-H2pma)2]n·4nH2O (1) and [Ag5(?6-H0.5tma)2(H2O)4]n·2nH2O (2) were generated from AgNO3 and pyromellitic (H4pma) or trimesic (H3tma) acid, also using N,N?-dimethylethanolamine (Hdmea) as a template. Both 1 and 2 feature the intricate 3D layer-pillared structures driven by distinct polycarboxylate blocks. Topological analysis revealed binodal nets with the flu and tcj/hc topology in 1 and 2, respectively. These CPs were used for fabricating new hybrid materials, namely, by doping the [ESOA]n biopolymer films with very low amounts of 1 and 2 (0.05, 0.1, and 0.5\%). Their antimicrobial activity and ability to impair bacterial biofilm formation were investigated in detail against both Gram-positive (Staphylococcus epidermidis and Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa and Escherichia coli) bacteria. Both silver(I) CPs and derived biopolymer films showed activity against all the tested bacteria in a concentration-dependent manner. Compound 1 exhibited a more pronounced activity, especially in preventing biofilm growth, with mean bacterial load reductions ranging from 3.7 to 4.3 log against the four bacteria (99.99\% bacterial eradication). The present work thus opens up antibiofilm applications of CP-doped biopolymers, providing new perspectives and very promising results for the design of functional biomaterials. | por |
dc.description.sponsorship | This work has been supported by the Foundation for Science and Technology (FCT) and Portugal 2020 (projects PTDC/ QUI-QIN/29697/2017, LISBOA-01-0145-FEDER-029697, UIDB/00100/2020, UIDP/00100/2020, IPL/2020/HyBioPol, and REM2013), contracts under DL nos. 57/2016 and CEECIND/02725/2018. This paper has been supported by the RUDN University Strategic Academic Leadership Program. We thank Dr. Rita Pacheco for experimental assistance and Eng. Mário A. P. Dias for ICP−OES analyses. | por |
dc.language.iso | eng | por |
dc.publisher | American Chemical Society | por |
dc.relation | PTDC/QUI-QIN/29697/2017 | por |
dc.relation | LISBOA-01-0145-FEDER-029697 | por |
dc.relation | UIDB/00100/2020 | por |
dc.relation | UIDP/00100/2020 | por |
dc.relation | IPL/2020/HyBioPol | por |
dc.relation | REM2013 | por |
dc.relation | CEECIND/02725/2018 | por |
dc.rights | restrictedAccess | por |
dc.subject | Metal-organic frameworks | por |
dc.subject | Silver | por |
dc.subject | Crystal structures | por |
dc.subject | Hybrid materials | por |
dc.subject | Antibacterial activity | por |
dc.subject | Biopolymers | por |
dc.subject | Biofilms | por |
dc.title | Silver(I) coordination polymers immobilized into biopolymer films for antimicrobial applications | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://pubs.acs.org/journal/aamick | por |
dc.comments | CEB54275 | por |
oaire.citationStartPage | 12836 | por |
oaire.citationEndPage | 12844 | por |
oaire.citationIssue | 11 | por |
oaire.citationConferencePlace | United States | - |
oaire.citationVolume | 13 | por |
dc.date.updated | 2021-10-09T11:45:03Z | - |
dc.identifier.eissn | 1944-8252 | por |
dc.identifier.doi | 10.1021/acsami.0c19446 | por |
dc.date.embargo | 10000-01-01 | - |
dc.identifier.pmid | 33705111 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | ACS Applied Materials & Interfaces | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_54275_1.pdf Acesso restrito! | 3,37 MB | Adobe PDF | Ver/Abrir |