Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/73901
Título: | Emerging optical materials in sensing and discovery of bioactive compounds |
Autor(es): | Vaz, Raquel Valpradinhos, Beatriz Frasco, Manuela Sales, M. G. F. |
Palavras-chave: | Biosensors Optical detection Aquatic biotoxins Drug discovery Bioactive compounds |
Data: | 27-Ago-2021 |
Editora: | MDPI |
Revista: | Sensors |
Citação: | Vaz, R.; Valpradinhos, Beatriz; Frasco, Manuela; Sales, M. G. F., Emerging optical materials in sensing and discovery of bioactive compounds. Sensors, 21(17), 5784, 2021 |
Resumo(s): | Optical biosensors are used in numerous applications and analytical fields. Advances in these sensor platforms offer high sensitivity, selectivity, miniaturization, and real-time analysis, among many other advantages. Research into bioactive natural products serves both to protect against potentially dangerous toxic compounds and to promote pharmacological innovation in drug discovery, as these compounds have unique chemical compositions that may be characterized by greater safety and efficacy. However, conventional methods for detecting these biomolecules have drawbacks, as they are time-consuming and expensive. As an alternative, optical biosensors offer a faster, simpler, and less expensive means of detecting various biomolecules of clinical interest. In this review, an overview of recent developments in optical biosensors for the detection and monitoring of aquatic biotoxins to prevent public health risks is first provided. In addition, the advantages and applicability of these biosensors in the field of drug discovery, including high-throughput screening, are discussed. The contribution of the investigated technological advances in the timely and sensitive detection of biotoxins while deciphering the pathways to discover bioactive compounds with great health-promoting prospects is envisaged to meet the increasing demands of healthcare systems. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/73901 |
DOI: | 10.3390/s21175784 |
ISSN: | 1424-8220 |
e-ISSN: | 1424-8220 |
Versão da editora: | https://www.mdpi.com/1424-8220/21/17/5784 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_54588_1.pdf | 4,06 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons