Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/72748
Título: | Synthesis of 2-(aminophenyl)adenine derivatives: a simple protocol using the classical iron powder/acetic acid reduction methodology |
Autor(es): | Rocha, A. Proença, M. Fernanda R. P. Carvalho, M. Alice |
Palavras-chave: | 2-(aminophenyl)adenine derivatives Nitro reduction Chemoselectivity Purine derivatives 2-aryladenine derivatives |
Data: | 2020 |
Editora: | Canadian Science Publishing |
Revista: | Canadian Journal of Chemistry |
Citação: | Rocha, A., Proença, M. F., & Carvalho, M. A. (2020). Synthesis of 2-(aminophenyl) adenine derivatives: a simple protocol using the classical iron powder/acetic acid reduction methodology. Canadian Journal of Chemistry, 98(3), 145-150 |
Resumo(s): | 2-(Nitrophenyl)adenine derivatives were isolated from the reaction of 5-amino-4-amidino-imidazoles with nitro-benzaldehydes. The conversion of the nitro derivatives to 2-(aminophenyl)adenine derivatives was performed using iron/acetic acid as reducing agent, in 70% aqueous ethanol. The products were isolated in good yield and the isolation protocol involves simple filtration and extraction procedures. This methodology is compatible with the presence of functional groups such as amines, ethers, halofluorides, and halochlorides. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/72748 |
DOI: | 10.1139/cjc-2019-0270 |
ISSN: | 0008-4042 |
Versão da editora: | https://cdnsciencepub.com/doi/abs/10.1139/cjc-2019-0270 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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cjc-2019-0270.pdf Acesso restrito! | 274,91 kB | Adobe PDF | Ver/Abrir |