Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/70373
Título: | Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
Autor(es): | Peixoto, Tânia Paiva, M. C. Marques, António T. Lopes, Maria A. |
Palavras-chave: | biocompatibility and biodegradability composite scaffolds graphene mechanical properties tendon and ligament repair |
Data: | Dez-2020 |
Editora: | Wiley |
Revista: | Advanced Engineering Materials |
Citação: | Peixoto, T., Paiva, M. C., Marques, A. T., & Lopes, M. A. (2020). Potential of Graphene–Polymer Composites for Ligament and Tendon Repair: A Review. Advanced Engineering Materials, 22(12), 2000492 |
Resumo(s): | Tendon/ligament injuries are debilitating conditions that affect the life quality of a great percentage of the adult population. Several challenges still have to be addressed regarding the repair of these tissues, as current treatments show limited success. The use of biocompatible and biodegradable polymeric scaffolds potentially helps accomplish a complete and long-term functional repair but, unfortunately, these materials lack adequate mechanical properties to be used in such demanding applications. Graphene is a subject of interest for tissue-repair applications due to its electrical conductivity and mechanical properties. If incorporated adequately, it may significantly improve the physical properties of the composite, even at small loadings. Furthermore, graphene presents a biocompatible surface that may enhance cell adhesion, proliferation and differentiation and demonstrates promising outcomes in several in vitro and in vivo biological applications. Therefore, herein, the potential of graphene materials for the reinforcement of biodegradable polymers of interest for tendon/ligament repair is explored. The effect of graphene on relevant features such as mechanical properties, biodegradability, and biocompatibility is revised, to understand the feasibility of these composites to fulfill the requirements associated with these tissues and conclude how their applicability is extended to this field. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/70373 |
DOI: | 10.1002/adem.202000492 |
ISSN: | 1438-1656 |
e-ISSN: | 1527-2648 |
Versão da editora: | https://onlinelibrary.wiley.com/doi/abs/10.1002/adem.202000492 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | IPC - Artigos em revistas científicas internacionais com arbitragem |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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AdvEngMat 2000 Tânia.pdf | 5,3 MB | Adobe PDF | Ver/Abrir |