Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/68758
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Pombo, Bruno | por |
dc.contributor.author | Ferreira, Ana Cristina | por |
dc.contributor.author | Cardoso, Pedro | por |
dc.contributor.author | Oliveira, António | por |
dc.date.accessioned | 2020-12-29T23:18:57Z | - |
dc.date.available | 2020-12-29T23:18:57Z | - |
dc.date.issued | 2020-11 | - |
dc.date.submitted | 2019-03 | - |
dc.identifier.issn | 0940-6719 | por |
dc.identifier.uri | https://hdl.handle.net/1822/68758 | - |
dc.description.abstract | Purpose Primary osteosarcoma of the spine is a rare osseous tumour. En bloc resection, in contrast to intralesional resection, is the only procedure able to provide Enneking appropriate (EA) margins, which has improved local control and survival of patients with primary osteosarcoma of the spine. The objective of this study is to compare the risk of local recurrence, metastases development and survival in patients with primary osteosarcoma of the spine submitted to Enneking appropriate (EA) and Enneking inappropriate (EI) procedures. Methods A systematic search was performed on EBSCO, PubMed and Web of Science, between 1966 and 2018, to identify studies evaluating patients submitted to resection of primary osteosarcoma of the spine. Two reviewers independently assessed all reports. The outcomes were local recurrence, metastases development and survival at 12, 24 and 60 months. Results Five studies (108 patients) were included for systematic review. These studies support the conclusion that EA procedure has a lower local recurrence rate (RR 0.33, 95% CI 0.17-0.66), a lower metastases development rate (RR 0.39, 95% CI 0.17-0.89) and a higher survival rate at 24 months (RR 1.78, 95% CI 1.24-2.55) and 60 months (RR 1.97, 95% CI 1.14-3.42) of follow-up; however, at 12 months, there is a non-significant difference. Conclusions EA procedure increases the ratio of remission and survival after 24 months of follow-up. Multidisciplinary oncologic groups should weigh the morbidity of an en bloc resection, knowing that in the first year the probability of survival is the same for EA and EI procedures. Graphic abstract These slides can be retrieved under Electronic Supplementary Material. | eng |
dc.language.iso | eng | por |
dc.publisher | Springer | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Enneking margins | por |
dc.subject | Local recurrence | por |
dc.subject | Metastatic disease | por |
dc.subject | Osteosarcoma | por |
dc.subject | Primary spine tumours | por |
dc.subject | Survival | por |
dc.title | Clinical effectiveness of Enneking appropriate versus Enneking inappropriate procedure in patients with primary osteosarcoma of the spine: a systematic review with meta-analysis | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://link.springer.com/article/10.1007/s00586-019-06099-7 | por |
oaire.citationStartPage | 238 | por |
oaire.citationEndPage | 247 | por |
oaire.citationIssue | 2 | por |
oaire.citationVolume | 29 | por |
dc.identifier.eissn | 1432-0932 | por |
dc.identifier.doi | 10.1007/s00586-019-06099-7 | por |
dc.identifier.pmid | 31410619 | por |
dc.subject.fos | Ciências Médicas::Outras Ciências Médicas | por |
dc.subject.fos | Ciências Naturais::Matemáticas | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | European Spine Journal | por |
oaire.version | AM | por |
Aparece nas coleções: | CMAT - Artigos em revistas com arbitragem / Papers in peer review journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Clinical effectiveness of Enneking(RepositoriUM).pdf | 531,79 kB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons