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https://hdl.handle.net/1822/67634
Título: | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
Autor(es): | Rolanda, Carla Lima, Estêvão Augusto Rodrigues de Silva, David Moreira, Ivone Pêgo, José M. Macedo, Guilherme Correia-Pinto, Jorge |
Palavras-chave: | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
Data: | Dez-2009 |
Editora: | Elsevier 1 |
Revista: | Gastrointestinal Endoscopy |
Citação: | Rolanda, C., Lima, E., Silva, D., Moreira, I., et. al. (2009). In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video). Gastrointestinal endoscopy, 70(6), 1137-1145 |
Resumo(s): | Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Background: Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Objective: To evaluate the reliability of the OTSC system in vivo after transgastric testicular vessel ligation (varicocelectomy model). Design: There were 3 experimental groups (5 animals in each): groups 1 and 3, gastrotomy dilation up to 18 mm, surgery was performed with a double-channel endoscope; group 2, gastrotomy dilation up to 13 mm, surgery was performed with a single-channel endoscope. Setting: Surgical Sciences Research Domain, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. Interventions: Bilateral testicular vessel ligation by transgastric access. Gastrotomy closed with the largest version of OTSC system (12 mm): a single clip in groups 1 and 2, and 2 clips in group 3. Animals were monitored for 2 weeks, killed, and submitted for necropsy. Main Outcome Measurements: Adequacy of closure and healing after the use of the OTSC system. Statistical analysis. Results: Vessel ligation was easily achieved in all groups. Although differences in the complication rate did not reach statistical significance (P Z .099), there was a clear tendency for a better prognosis in groups 2 and 3 than group 1. In fact, only 2 animals from group 1 had complications related to incomplete gastrotomy closure. Limitations: Small number of animals per group; nonrandomized study. Conclusions: The OTSC system was shown to be easy and efficient for gastrotomy closure in a survival experimental model of varicocelectomy, when correctly matching the gastrotomy size with the clip size and/or number |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/67634 |
DOI: | 10.1016/j.gie.2009.04.054 |
ISSN: | 0016-5107 |
Versão da editora: | https://www.sciencedirect.com/science/article/pii/S0016510709019087 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Rolanda-2009-In-vivo-assessment-of-gastrotomy-cl.pdf Acesso restrito! | 1,47 MB | Adobe PDF | Ver/Abrir |