Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/67519
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Almeida, Maria Inês | por |
dc.contributor.author | Reis, R. M. | por |
dc.contributor.author | Calin, George A. | por |
dc.date.accessioned | 2020-10-15T14:34:08Z | - |
dc.date.available | 2020-10-15T14:34:08Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | Almeida, M. I., Reis, R. M., & Calin, G. A. (2010). MYC-microRNA-9-metastasis connection in breast cancer. Cell research, 20(6), 603-604 | por |
dc.identifier.issn | 1001-0602 | - |
dc.identifier.uri | https://hdl.handle.net/1822/67519 | - |
dc.description.abstract | [Excerpt] Metastasis accounts for more than 90% of cancer patients’ mortality. The metastatic process involves multiple steps [1]. Initially, cancer cells from the primary tumor invade adjacent stroma. To acquire this capacity, cells undergo a process called epithelial-mesenchymal transition (EMT), in which cells in re-sponse to signals from the surrounding stroma, undergo a switch between cell phenotypes and acquire mesenchymal properties and show reduced intercel-lular adhesion, allowing cells to be-come motile. Then cells enter systemic circulation, either through the blood or lymph, and finally extravasate into the parenchyma of distant tissues, where they form micrometastasis and prolifer-ate to form secondary tumors [2]. [...] | - |
dc.language.iso | eng | por |
dc.publisher | Springer Nature | por |
dc.rights | openAccess | por |
dc.subject | Breast Neoplasms | por |
dc.subject | Cadherins | por |
dc.subject | Female | por |
dc.subject | Gene Expression Regulation, Neoplastic | por |
dc.subject | Humans | por |
dc.subject | MicroRNAs | por |
dc.subject | Neovascularization, Pathologic | por |
dc.subject | Neuroblastoma | por |
dc.subject | Proto-Oncogene Proteins c-myc | por |
dc.subject | Signal Transduction | por |
dc.subject | Vascular Endothelial Growth Factor A | por |
dc.subject | beta Catenin | por |
dc.title | MYC-microRNA-9-metastasis connection in breast cancer | por |
dc.type | journalEditorial | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.nature.com/articles/cr201070 | por |
oaire.citationStartPage | 603 | por |
oaire.citationEndPage | 604 | por |
oaire.citationIssue | 6 | por |
oaire.citationVolume | 20 | por |
dc.identifier.eissn | 1748-7838 | - |
dc.identifier.doi | 10.1038/cr.2010.70 | por |
dc.identifier.pmid | 20502442 | por |
dc.subject.fos | Ciências Médicas::Medicina Básica | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Cell Research | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Almeida-2010-Myc-microrna--metastasis-connection.pdf | 352,15 kB | Adobe PDF | Ver/Abrir |