Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/66141
Título: | Efficacy and cytotoxicity of binary mixtures as root canal filling solvents |
Autor(es): | Ferreira, Inês Grenho, Liliana Gomes, Pedro Braga, A. C. Fernandes, Maria Helena Lopes, Maria Ascensão Pina-Vaz, Irene |
Palavras-chave: | endodontic material epoxy resin-based root canal sealer gutta-percha retreatment root canal filling materials solvents ultrasonic agitation |
Data: | 2020 |
Editora: | Multidisciplinary Digital Publishing Institute |
Revista: | Materials |
Citação: | Ferreira, I.; Grenho, L.; Gomes, P.; Braga, A.C.; Fernandes, M.H.; Lopes, M.A.; Pina-Vaz, I. Efficacy and Cytotoxicity of Binary Mixtures as Root Canal Filling Solvents. Materials 2020, 13, 3237. |
Resumo(s): | Objectives: This study reports the efficacy of two solvent mixtures on the dissolution of gutta-percha and AH Plus sealer, together with the cytotoxicity. Methods: Methyl ethyl ketone (MEK), orange oil, tetrachloroethylene, MEK/tetrachloroethylene (1:1), MEK/orange oil (1:1), and chloroform (control) were tested. Twelve groups (<i>n</i> = 15) of standardized stainless-steel molds filled with softened gutta-percha cones and twelve (<i>n</i> = 15) filled with AH Plus were immersed in the corresponding mixture or individual solvent, in an ultrasonic bath, for either 2 or 5 min. The effect of the solvents was assessed qualitatively by a topographical analysis (scanning electron microscopy) and chemical analysis (Fourier transform infrared spectroscopy), and quantitatively by a weight loss and viscoelastic property (dynamic mechanical analysis) evaluation. The cytotoxicity was assessed on MG63 human osteoblastic cells. Results: The mixtures did not show the formation of new compounds. Both presented significantly higher efficacies compared to their individual solvents, suggesting a synergistic effect. Their dissolution efficacy was similar to that of chloroform, showing high cytocompatibility. Conclusions: The proposed strategy, incorporating ultrasound agitation and profiting from the synergy of adequate solvents, might enhance root canal cleanliness allowing a single-step procedure to dissolve gutta-percha and the sealer remnants, while assuring cytocompatibility with the periapical tissues. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/66141 |
DOI: | 10.3390/ma13143237 |
e-ISSN: | 1996-1944 |
Versão da editora: | https://www.mdpi.com/1996-1944/13/14/3237 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CAlg - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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materials-13-03237.pdf | 5,12 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons