Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/65541
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Campo DC | Valor | Idioma |
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dc.contributor.author | Sande, Maria | por |
dc.contributor.author | Çaykara, Tugçe | por |
dc.contributor.author | Silva, Carla Joana | por |
dc.contributor.author | Rodrigues, L. R. | por |
dc.date.accessioned | 2020-05-31T21:16:59Z | - |
dc.date.available | 2020-05-31T21:16:59Z | - |
dc.date.issued | 2020-02-05 | - |
dc.identifier.citation | Sande, Maria; Çaykara, Tugçe; Silva, Carla Joana; Rodrigues, Lígia R., New solutions to capture and enrich bacteria from complex samples. Medical Microbiology and Immunology, 209, 335-341, 2020 | por |
dc.identifier.issn | 0300-8584 | por |
dc.identifier.uri | https://hdl.handle.net/1822/65541 | - |
dc.description.abstract | Current solutions to diagnose bacterial infections though reliable are often time-consuming, laborious and need a specific laboratory setting. There is an unmet need for bedside accurate diagnosis of infectious diseases with a short turnaround time. Moreover, low-cost diagnostics will greatly benefit regions with poor resources. Immunoassays and molecular techniques have been used to develop highly sensitive diagnosis solutions but retaining many of the abovementioned limitations. The detection of bacteria in a biological sample can be enhanced by a previous step of capture and enrichment. This will ease the following process enabling a more sensitive detection and increasing the possibility of a conclusive identification in the downstream diagnosis. This review explores the latest developments regarding the initial steps of capture and enrichment of bacteria from complex samples with the ultimate goal of designing low cost and reliable diagnostics for bacterial infections. Some solutions use specific ligands tethered to magnetic constructs for separation under magnetic fields, microfluidic platforms and engineered nano-patterned surfaces to trap bacteria. Bulk acoustics, advection and nano-filters comprise some of the most innovative solutions for bacteria enrichment. | por |
dc.description.sponsorship | This research is affiliated to the VibrANT project that received funding from the EU Horizon 2020 Research and Innovation Programme under the Marie Sklowdowska-Curie Grant, agreement no 765042. In addition, MGS, TC and LRR acknowledge the fnancial support from Fundação para a Ciência e Tecnologia (FCT) under the scope of the strategic funding of UID/BIO/04469/2020 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684), through national funds and where applicable co-fnanced by the FEDER, within the PT2020 Partnership Agreement. The same authors also acknowledge BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020-Programa Operacional Regional do Norte. | por |
dc.language.iso | eng | por |
dc.publisher | Springer Nature | por |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/765042/EU | por |
dc.relation | UID/BIO/04469/2020 | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Diagnostics | por |
dc.subject | Bacteria capture | por |
dc.subject | Enrichment | por |
dc.subject | Detection limit | por |
dc.subject | Microfuidics | por |
dc.subject | Magnetic beads | por |
dc.subject | Magnetic nanoparticles | por |
dc.subject | Acoustophoresis | por |
dc.subject | Aptamer | por |
dc.subject | Bacteriophage | por |
dc.subject | Peptide | por |
dc.subject | Point-of-care | por |
dc.subject | Nano-patterning | por |
dc.subject | Microfluidics | por |
dc.title | New solutions to capture and enrich bacteria from complex samples | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.springer.com/journal/430 | por |
dc.comments | CEB53459 | por |
oaire.citationStartPage | 335 | por |
oaire.citationEndPage | 341 | por |
oaire.citationIssue | 3 | por |
oaire.citationVolume | 209 | por |
dc.date.updated | 2020-05-30T13:06:05Z | - |
dc.identifier.eissn | 1432-1831 | por |
dc.identifier.doi | 10.1007/s00430-020-00659-1 | por |
dc.identifier.pmid | 32025887 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Medical Microbiology and Immunology | por |
oaire.version | VoR | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_53459_1.pdf | 784 kB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons