Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/65218
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Campo DC | Valor | Idioma |
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dc.contributor.author | Baldim, Iara | por |
dc.contributor.author | Rosa, Débora M. | por |
dc.contributor.author | Souza, Claudia R. F. | por |
dc.contributor.author | Ana, Raquel da | por |
dc.contributor.author | Durazzo, Alessandra | por |
dc.contributor.author | Lucarini, Massimo | por |
dc.contributor.author | Santini, Antonello | por |
dc.contributor.author | Souto, Eliana B. | por |
dc.contributor.author | Oliveira, Wanderley P. | por |
dc.date.accessioned | 2020-05-05T12:53:51Z | - |
dc.date.available | 2020-05-05T12:53:51Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Baldim, Iara; Rosa, Débora M.; Souza, Claudia R. F.; Ana, Raquel da; Durazzo, Alessandra; Lucarini, Massimo; Santini, Antonello; Souto, Eliana; Oliveira, Wanderley P., Factors affecting the retention efficiency and physicochemical properties of spray dried lipid nanoparticles loaded with lippia sidoides essential oil. Biomolecules, 10(5), 693, 2020 | por |
dc.identifier.uri | https://hdl.handle.net/1822/65218 | - |
dc.description.abstract | Essential oils (EOs) are widely used in various industrial sectors but can present several instability problems when exposed to environmental factors. Encapsulation technologies are effective solutions to improve EOs properties and stability. Currently, the encapsulation in lipid nanoparticles has received significant attention, due to the several recognized advantages over conventional systems. The study aimed to investigate the influence of the lipid matrix composition and spray-drying process on the physicochemical properties of the lipid-based nanoparticles loaded with Lippia sidoides EO and their retention efficiency for the oil. The obtained spray-dried products were characterized by determination of flow properties (Carr Index: from 25.0% to 47.93%, and Hausner ratio: from 1.25 to 1.38), moisture (from 3.78% to 5.20%), water activity (<0.5), and powder morphology. Zeta potential, mean particle size and polydispersity index, of the redispersed dried product, fell between 25.9 mV and 30.9 mV, 525.3 nm and 1143 nm, and 0.425 and 0.652, respectively; showing slight differences with the results obtained prior to spray-drying (from 16.4 mV to 31.6 mV; 147 nm to 1531 nm; and 0.459 to 0.729). Thymol retention in the dried products was significantly lower than the values determined for the liquid formulations and was affected by the drying of nanoparticles. | por |
dc.description.sponsorship | I.B. acknowledges CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) for the financial support (88887.368385/2019-00). E.B.S. acknowledges the Portuguese Science and Technology Foundation (FCT) for the funded projects M-ERA-NET/0004/2015 (PAIRED) and UIDB/04469/2020 (strategic fund). WPO acknowledges the São Paulo Research Foundation (FAPESP) for the financial support (Grant N. 2018/26069-0 and 2011/10333-1). | por |
dc.language.iso | eng | por |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | por |
dc.relation | UIDB/04469/2020 | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by-nd/4.0/ | por |
dc.subject | lipid nanoparticles | por |
dc.subject | nanostructured lipid carriers | por |
dc.subject | spray-drying | por |
dc.subject | essential oil | por |
dc.subject | Lippia sidoides | por |
dc.subject | pepper rosemary | por |
dc.title | Factors affecting the retention efficiency and physicochemical properties of spray dried lipid nanoparticles loaded with lippia sidoides essential oil | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.mdpi.com/journal/biomolecules | por |
dc.comments | CEB53656 | por |
oaire.citationIssue | 5 | por |
oaire.citationVolume | 10 | por |
dc.date.updated | 2020-05-02T11:11:59Z | - |
dc.identifier.eissn | 2218-273X | por |
dc.identifier.doi | 10.3390/biom10050693 | por |
dc.identifier.pmid | 32365717 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biomolecules | por |
oaire.version | VoR | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_53656_1.pdf | 1,61 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons