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https://hdl.handle.net/1822/62448| Título: | Stereoselective synthesis of 5-substituted hexahydropyrroquinolines-2,3-diol from functionalized tetrahydroquinolines |
| Autor(es): | Drogalin, Artem Alves, Maria José Castro, Tarsila Gabriel |
| Data: | 20-Nov-2019 |
| Citação: | Drogalin, Artem; Alves, Maria José; Castro, T., Stereoselective synthesis of 5-substituted hexahydropyrroquinolines-2,3-diol from functionalized tetrahydroquinolines. XXV Encontro Galego-Português de Química. No. QO25, Santiago de Compostela, Spain, Nov 20-22, 358, 2019. |
| Resumo(s): | [Excerpt] 1,2,3,4-Tetrahydroquinolines (THQ) had shown diverse biological activities such as antiarrhythmic, cardiovascular, anticancer and immunosuppressor agents [1]. In this work tetrahydroquinolines 2 were synthesized by Povarov’s reaction [3] from Schiff base 1, being subsequently cyclized to hexahydropyrroquinolines-2,3-diol (HHPQ) 3a-c using trivial reagents. Some new THQ bearing a trihydroxypropyl arm have already been synthetized. [...] |
| Tipo: | Resumo em ata de conferência |
| URI: | https://hdl.handle.net/1822/62448 |
| Versão da editora: | https://www.encontrogalegoportugues.org/ |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
| Aparece nas coleções: |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| document_52223_1.pdf | 313,65 kB | Adobe PDF | Ver/Abrir | |
| document_52223_2.pdf | 305,96 kB | Adobe PDF | Ver/Abrir |
