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https://hdl.handle.net/1822/62317
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Campo DC | Valor | Idioma |
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dc.contributor.author | Pereira, Patrícia | por |
dc.contributor.author | Korbas, Malgorzata | por |
dc.contributor.author | Pereira, Vitória | por |
dc.contributor.author | Cappello, Tiziana | por |
dc.contributor.author | Maisano, Maria | por |
dc.contributor.author | Canário, João | por |
dc.contributor.author | Almeida, Armando | por |
dc.contributor.author | Pacheco, Mário | por |
dc.date.accessioned | 2019-11-21T16:49:52Z | - |
dc.date.available | 2024-01-01T07:00:34Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 0304-4165 | - |
dc.identifier.uri | https://hdl.handle.net/1822/62317 | - |
dc.description.abstract | Neuronal and sensory toxicity of mercury (Hg) compounds has been largely investigated in humans/mammals with a focus on public health, while research in fish is less prolific and dispersed by different species. Well-established premises for mammals have been governing fish research, but some contradictory findings suggest that knowledge translation between these animal groups needs prudence [e.g. the relative higher neurotoxicity of methylmercury (MeHg) vs. inorganic Hg (iHg)]. Biochemical/physiological differences between the groups (e.g. higher brain regeneration in fish) may determine distinct patterns. This review undertakes the challenge of identifying sensitive cellular targets, Hg-driven biochemical/physiological vulnerabilities in fish, while discriminating specificities for Hg forms. | por |
dc.description.sponsorship | Thanks are due for the financial support to CESAM (UID/AMB/50017/2019), to FCT/MEC through national funds, and the co-funding by the FEDER, within the PT2020 Partnership Agreement and Compete 2020. Patrícia Pereira acknowledges the support of FCT through the post-doctoral research grants (SFRH/BPD/69563/2010 and SFRH/BPD/107718/2015). Currently, Patrícia Pereira is funded by national funds (OE), through FCT – Fundação para a Ciência e a Tecnologia, I.P., in the scope of the framework contract foreseen in the numbers 4, 5 and 6 of the article 23, of the Decree-Law 57/2016, of August 29, changed by Law 57/2017, of July 19. The authors are also grateful to the Co-Editors Professor Cristina Carvalho and Professor Michael Aschner for the opportunity to publish this article in a special issue of BBAGEN organized under their supervision. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | UID/AMB/50017/2019 | por |
dc.relation | SFRH/BPD/107718/2015 | por |
dc.rights | restrictedAccess | por |
dc.subject | Aquatic toxicology | por |
dc.subject | Brain | por |
dc.subject | Fish | por |
dc.subject | Mercury | por |
dc.subject | Neurotoxicity | por |
dc.subject | Sensory organs | por |
dc.title | A multidimensional concept for mercury neuronal and sensory toxicity in fish - From toxicokinetics and biochemistry to morphometry and behavior | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.comments | 48 meses | por |
oaire.citationIssue | 12 | por |
oaire.citationVolume | 1863 | por |
dc.identifier.doi | 10.1016/j.bbagen.2019.01.020 | por |
dc.identifier.pmid | 30768958 | por |
dc.subject.fos | Ciências Médicas::Ciências da Saúde | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biochimica et Biophysica Acta (BBA). General Subjects | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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1-s2.0-S0304416519300261-main.pdf | 2,06 MB | Adobe PDF | Ver/Abrir |