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https://hdl.handle.net/1822/62166
Título: | Early vascular ageing in translation: from laboratory investigations to clinical applications in cardiovascular prevention |
Autor(es): | Nilsson, Peter M. Boutouyrie, Pierre Cunha, Pedro Kotsis, Vasilios Narkiewicz, Krzysztof Parati, Gianfranco Rietzschel, Ernst Scuteri, Angelo Laurent, Stephane |
Palavras-chave: | Aging Blood Flow Velocity Blood Pressure Blood Pressure Determination Cardiovascular Diseases Cardiovascular System Cognition Disorders Collagen Elasticity Hemodynamics Humans Risk Vascular Stiffness ageing arterial stiffness cognition hyperglycemia hypertension metabolism microcirculation |
Data: | Ago-2013 |
Editora: | Lippincott, Williams & Wilkins |
Revista: | Journal of Hypertension |
Citação: | Nilsson, P. M., Boutouyrie, P., Cunha, P., Kotsis, V., et. al.(2013). Early vascular ageing in translation: from laboratory investigations to clinical applications in cardiovascular prevention. Journal of hypertension, 31(8), 1517-1526. |
Resumo(s): | The ageing of the vascular tree is a fundamental reflection of biological ageing in general and a determinant of organ function. In the arterial wall this is characterized by a reduction in the elastin content, as well as by an increased content of collagen and its cross-linkages, leading to increased arterial stiffness and elevated central as well as brachial blood pressure, accompanied by increased SBP variability. In recent years a better understanding of these processes have led to the proposal of a condition named early vascular ageing (EVA) in patients with increased arterial stiffness for their age and sex. This is a condition that could increase cardiovascular risk and is associated with various degrees of cognitive dysfunction, as well as other features of biological ageing. This brief review aims to give an update on EVA and how the concept can be used in clinical practice. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/62166 |
DOI: | 10.1097/HJH.0b013e328361e4bd |
ISSN: | 0263-6352 |
e-ISSN: | 1473-5598 |
Versão da editora: | https://journals.lww.com/jhypertension/Abstract/2013/08000/Early_vascular_ageing_in_translation___from.3.aspx |
Arbitragem científica: | yes |
Acesso: | Acesso restrito autor |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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nilsson2013.pdf Acesso restrito! | 313,67 kB | Adobe PDF | Ver/Abrir |