Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/51440
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Campo DC | Valor | Idioma |
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dc.contributor.author | Vecino, Xanel | por |
dc.contributor.author | Rodríguez-López, L. | por |
dc.contributor.author | Ferreira, Débora Carina Gonçalves Abreu | por |
dc.contributor.author | Cruz, J. M. | por |
dc.contributor.author | Moldes, A. B. | por |
dc.contributor.author | Rodrigues, L. R. | por |
dc.date.accessioned | 2018-03-02T14:32:49Z | - |
dc.date.available | 2018-03-02T14:32:49Z | - |
dc.date.issued | 2018-04 | - |
dc.identifier.citation | Vecino, Xanel; Rodríguez-López, L.; Ferreira, Débora; Cruz, J. M.; Moldes, A. B.; Rodrigues, Lígia R., Bioactivity of glycolipopeptide cell-bound biosurfactants against skin pathogens. International Journal of Biological Macromolecules, 109, 971-979, 2018 | por |
dc.identifier.issn | 0141-8130 | por |
dc.identifier.uri | https://hdl.handle.net/1822/51440 | - |
dc.description | "Available online 21 November 2017" | por |
dc.description.abstract | The antimicrobial and anti-adhesive activities of the cell-bound biosurfactants, produced by Lactobacillus pentosus (PEB), characterized as glycolipopeptide macromolecules, were evaluated against several microorganisms present in the skin microflora, envisaging its potential use as a natural ingredient in cosmetic and personal care formulations. Their performance was compared with another cell-bound biosurfactants also characterized as glycolipopeptides produced by Lactobacillus paracasei (PAB). At concentrations of 50 mg/mL, the PEB showed an important antimicrobial activity against Pseudomonas aeruginosa (85% when extracted with phosphate buffer (PB) and 100% when extracted with phosphate buffer saline (PBS)), Streptococcus agalactiae (100% for both extracts), Staphylococcus aureus (67% when extracted with PBS and 100% when extracted with PB), Escherichia coli (72% when extracted with PB and 89% when extracted with PBS), Streptococcus pyogenes (about 85% for both extracts) and Candida albicans (around 70% for both extracts), comparable with that obtained for the PAB. However, at lower concentrations the PAB exhibited in general higher antimicrobial activities. Biosurfactants produced by both microorganisms also showed significant anti-adhesive properties against all the microorganisms under study, except for E. coli and C. albicans (less than 30%). Overall, these cell-bound biosurfactants could be used as potential antimicrobial and anti-adhesive agents in cosmetic and pharmaceutical formulations. | por |
dc.description.sponsorship | This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, COMPETE 2020 (POCI01-0145-FEDER-006684), the Project MultiBiorefinery − Multipurposestrategies for broadband agro-forest and fisheries byproducts valorisation: a step forward for a truly integrated biorefinery (POCI-01-0145-FEDER-016403) and the project RECI/BBBEBI/0179/2012 (FCOMP-01-0124-FEDER-027462), as well as X. Vecino post-doctoral grant (SFRH/BPD/101476/2014). Also, L. Rodríguez-López acknowledges to the Spanish Ministry of Education, Culture and Sport for her pre-doctoral fellowship (FPU15/00205). | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147337/PT | por |
dc.rights | openAccess | por |
dc.subject | Lactobacilli | por |
dc.subject | Antimicrobial | por |
dc.subject | Anti-adhesive | por |
dc.title | Bioactivity of glycolipopeptide cell-bound biosurfactants against skin pathogens | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.elsevier.com/locate/issn/01418130 | por |
dc.comments | CEB47276 | por |
oaire.citationStartPage | 971 | por |
oaire.citationEndPage | 979 | por |
oaire.citationConferencePlace | Netherlands | - |
oaire.citationVolume | 109 | por |
dc.date.updated | 2018-02-18T13:12:24Z | - |
dc.identifier.eissn | 1879-0003 | por |
dc.identifier.doi | 10.1016/j.ijbiomac.2017.11.088 | por |
dc.identifier.pmid | 29162463 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | International Journal of Biological Macromolecules | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_47276_1.pdf | 2,34 MB | Adobe PDF | Ver/Abrir |