Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/51097
Título: | Blood flow visualization and measurements in microfluidic devices fabricated by a micromilling technique |
Autor(es): | Singhal, Jaron Pinho, Diana Lopes, Raquel Sousa, Patricia C. Garcia, Valdemar Schütte, Helmut Lima, Rui Alberto Madeira Macedo Gassmann, Stefan |
Palavras-chave: | Biomedical applications Blood cells Cell-free layer Cells separation Micromilling Microfluidic devices |
Data: | 2015 |
Editora: | Bentham Science Publishers |
Revista: | Micro and Nanosystems |
Resumo(s): | The most common and used technique to produce microfluidic devices for biomedical applications is the soft-lithography. However, this is a high cost and time-consuming technique. Recently, manufacturers were able to produce milling tools smaller than 100 m and consequently have promoted the ability of the micromilling machines to fabricate microfluidic devices capable of performing cell separation. In this work, we show the ability of a micromilling machine to manufacture microchannels down to 30 m and also the ability of a microfluidic device to perform partial separation of red blood cells from plasma. Flow visualization and measurements were performed by using a high-speed video microscopy system. Advantages and limitations of the micromilling fabrication process are also presented. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/51097 |
DOI: | 10.2174/1876402908666160106000332 |
ISSN: | 1876-4029 |
e-ISSN: | 1876-4037 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | DEM - Artigos em revistas de circulação internacional com arbitragem científica |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Jaron_MNS_2015.pdf | 992,05 kB | Adobe PDF | Ver/Abrir |