Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/48152
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Silva, Joana M. | por |
dc.contributor.author | Rodrigues, Luísa Cidália Guimarães | por |
dc.contributor.author | Silva, Simone Santos | por |
dc.contributor.author | Reis, R. L. | por |
dc.contributor.author | Duarte, Ana Rita C. | por |
dc.date.accessioned | 2017-12-11T13:40:14Z | - |
dc.date.issued | 2018 | - |
dc.date.submitted | 2017-11 | - |
dc.identifier.citation | Silva J. M., Rodrigues L.C., Silva S. S., Reis R. L., Duarte A. R. C. Engineered tubular structures based on chitosan for tissue engineering applications, Journal of Biomaterials Applications, pp. 1-12, doi:10.1177/0885328217744698, 2018. | por |
dc.identifier.issn | 0885-3282 | por |
dc.identifier.uri | https://hdl.handle.net/1822/48152 | - |
dc.description.abstract | The development of versatile tubular structures is a subject of broad interest in tissue engineering applications. Herein, we demonstrate the production of tubular structures based on chitosan through a combination of dipping, freeze-drying and supercritical technology approaches. The combination of these techniques yields versatile tubes with a perfectly defined hollow imprint, which upon chemical cross-linking with genipin acquire enhanced mechanical properties (Young Modulus (E) and ultimate tensile stress (smax)), as well as improved stability in wet conditions. The biological performance reveals that cells remain attached, well-spread and viable on the surface of cross-linked tubes. As so, is envisioned that our methodology opens up new avenues on tissue engineering approaches, where the design of tubular structures with tuned length, diameter and elasticity is required. | por |
dc.description.sponsorship | The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The research leading to these results has received funding from the Portuguese Foundation for Science and Technology (FCT) by PTDC/CTM-BIO/4706/2014 and SFRH/BPD/ 93697/2013 and from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement number REGPOT-CT2012- 316331-POLARIS. | por |
dc.language.iso | eng | por |
dc.publisher | SAGE Publications | por |
dc.relation | PTDC/CTM-BIO/4706/2014 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F93697%2F2013/PT | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/316331/EU | por |
dc.rights | restrictedAccess | por |
dc.subject | Biofunctionality | por |
dc.subject | Biomaterials | por |
dc.subject | Biomimetic | por |
dc.subject | Chitosan | por |
dc.subject | Tissue engineering | por |
dc.title | Engineered tubular structures based on chitosan for tissue engineering applications | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://journals.sagepub.com/eprint/FZDEhJHScaHJwA35UIII/full | por |
dc.comments | http://3bs.uminho.pt/node/19256 | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 12 | por |
oaire.citationIssue | 7 | por |
oaire.citationVolume | 32 | por |
dc.date.updated | 2017-12-11T12:01:18Z | - |
dc.identifier.eissn | 1530-8022 | por |
dc.identifier.doi | 10.1177/0885328217744698 | por |
dc.identifier.pmid | 29187013 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Biomaterials Applications | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
19256-Engineered tubular structures based on chitosan for tissue engineering applications.pdf Acesso restrito! | 1,65 MB | Adobe PDF | Ver/Abrir |