Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/45187
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Naves, Lucas | por |
dc.contributor.author | Dhand, Chetna | por |
dc.contributor.author | Almeida, Luís de | por |
dc.contributor.author | Rajamani, Lakshminarayanan | por |
dc.contributor.author | Ramakrishna, Seeram | por |
dc.contributor.author | Soares, Graça M. B. | por |
dc.date.accessioned | 2017-03-30T14:18:04Z | - |
dc.date.available | 2017-03-30T14:18:04Z | - |
dc.date.issued | 2017-02-06 | - |
dc.identifier.issn | 2194-0509 | por |
dc.identifier.uri | https://hdl.handle.net/1822/45187 | - |
dc.description.abstract | In past few decades, scientists have made tremendous advancement in the field of drug delivery systems (DDS), through transdermal pathway, as the skin represents a ready and large surface area for delivering drugs. Efforts are in progress to design efficient transdermal DDS that support sustained drug release at the targeted area for longer duration in the recommended therapeutic window without producing side-effects. Poly(lactic-co-glycolic acid) (PLGA) is one of the most promising Food and Drug Administration approved synthetic polymers in designing versatile drug delivery carriers for different drug administration routes, including transdermal drug delivery. The present review provides a brief introduction over the transdermal drug delivery and PLGA as a material in context to its role in designing drug delivery vehicles. Attempts are made to compile literatures over PLGA-based drug delivery vehicles, including microneedles, nanoparticles, and nanofibers and their role in transdermal drug delivery of different therapeutic agents. Different nanostructure evaluation techniques with their working principles are briefly explained. | por |
dc.description.sponsorship | RL thanks the funding support from Singapore National Research Foundation under its Translational and Clinical Research Flagship Programme (NMRC/TCR/008-SERI/2013) and administered by the Singapore Ministry of Health’s National Medical Research Council and Co-operative Basic Research Grant from the Singapore National Medical Research Council (Project No. NMRC/CBRG/0048/2013). | por |
dc.language.iso | eng | por |
dc.publisher | SpringerOpen | por |
dc.relation | Authors want to acknowledge financial support from CAPES foundation for the Ph.D. Grant with process number 13543/13-0, Brazilian Ministry of Education, Brazil. | por |
dc.relation | Authors also like to thank FEDER funds through Competitive Factors Operational Programme-COMPETE and national funds through FCT-Foundation for Science and Technology (POCI-01-0145-FEDER-007136) | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Drug delivery system | por |
dc.subject | Transdermal drug delivery | por |
dc.subject | PLGA | por |
dc.subject | Microneedles | por |
dc.subject | Electrospinning technique | por |
dc.title | Poly(lactic-co-glycolic) acid drug delivery systems through transdermal pathway : an overview | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://link.springer.com/article/10.1007%2Fs40204-017-0063-0 | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 11 | por |
oaire.citationIssue | 1-2 | por |
oaire.citationTitle | Progress in biomaterials | por |
oaire.citationVolume | 6 | por |
dc.identifier.doi | 10.1007/s40204-017-0063-0 | por |
dc.subject.fos | Engenharia e Tecnologia::Engenharia Médica | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Progress in biomaterials | por |
Aparece nas coleções: | DET/2C2T - Artigos em revistas internacionais com arbitragem científica |
Este trabalho está licenciado sob uma Licença Creative Commons