Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/40511
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Ferreira, Patrícia | por |
dc.contributor.author | Lopes, Marlene | por |
dc.contributor.author | Mota, M. | por |
dc.contributor.author | Belo, Isabel | por |
dc.date.accessioned | 2016-02-24T12:23:01Z | - |
dc.date.available | 2016-02-24T12:23:01Z | - |
dc.date.issued | 2016-06 | - |
dc.identifier.citation | Ferreira, P.; Lopes, Marlene; Mota, M.; Belo, Isabel, Oxygen mass transfer impact on citric acid production by Yarrowia lipolytica from crude glycerol. Biochemical Engineering Journal, 110, 35-42, 2016 | por |
dc.identifier.issn | 1369-703X | por |
dc.identifier.uri | https://hdl.handle.net/1822/40511 | - |
dc.description.abstract | Production of citric acid from crude glycerol from biodiesel industry, in batch cultures of Yarrowia lipolytica W29 was performed in a lab-scale stirred tank bioreactor in order to assess the effect of oxygen mass transfer rate in this bioprocess. An empirical correlation was proposed to describe oxygen volumetric mass transfer coefficient (kLa) as a function of operating conditions (stirring speed and specific air flow rate) and cellular density. kLa increased according with a power function with specific power input and superficial gas velocity, and slightly decreased with cellular density. The increase of initial kLa from 7 h-1 to 55 h-1 led to 7.8-fold increase of citric acid final concentration. Experiments were also performed at controlled dissolved oxygen (DO) and citric acid concentration increased with DO up to 60% of saturation. Thus, due to the simpler operation setting an optimal kLa than at controlled DO, it can be concluded that kLa is an adequate parameter for the optimization of citric acid production from crude glycerol by Y. lipolytica and to be considered in bioprocess scale-up. Our empirical correlation, considering the operating conditions and cellular density, will be a valid tool for this purpose. | por |
dc.description.sponsorship | This work was financially supported by Portuguese Foundation for Science Technology and the European Community fund FEDER through Program COMPETE under PhD grant SFRH/BD/72621/2010 attributed to Patricia Ferreira and Post-Doctoral grant SFRH/BPD/101034/2014 attributed to Marlene Lopes, also under the scope of the projects RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462), the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684). | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier B.V. | por |
dc.rights | openAccess | por |
dc.subject | Yarrowia lipolytica | por |
dc.subject | Citric acid | por |
dc.subject | Crude glycerol | por |
dc.subject | Oxygen volumetric mass transfer coefficient | por |
dc.subject | Dissolved oxygen concentration | por |
dc.title | Oxygen mass transfer impact on citric acid production by Yarrowia lipolytica from crude glycerol | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.elsevier.com/locate/issn/1369703X | por |
dc.comments | CEB34794 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 35 | por |
oaire.citationEndPage | 42 | por |
oaire.citationConferencePlace | Netherlands | - |
oaire.citationTitle | Biochemical Engineering Journal | por |
oaire.citationVolume | 110 | por |
dc.date.updated | 2016-02-21T12:02:56Z | - |
dc.identifier.eissn | 1369-703X | - |
dc.identifier.doi | 10.1016/j.bej.2016.02.001 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biochemical Engineering Journal | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_34794_1.pdf | 864 kB | Adobe PDF | Ver/Abrir |