Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/39110
Título: | Antifungal action of three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides |
Autor(es): | Maia, M. Gabriel, C. Cravo, S. Dias, Alice Ribeiro, A. Proença, M. Fernanda R. P. Cerqueira, F. Pinto, E. |
Palavras-chave: | Química Orgânica Química Terapêutica |
Data: | 1-Dez-2015 |
Resumo(s): | [Excerpt] The incidence of fungal infections has greatly increased in patients under sustained immunosuppression with considerable risk associated. Difficulties regarding prompt diagnosis and the limited therapeutic options dictate high mortality rates. Available antifungals display substantial toxicity, a predictable consequence of the cellular structure of the organisms involved, reduced spectrum of activity, and drug interactions. Our group had previously identified three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides 1 [aryl= phenyl (1a), 4-fluorophenyl (1b), 3fluorophenyl (1c)] as potent antifungal agents.1 (...) |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/39110 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CDQuim - Comunicações e Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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QOT_Antifungal action of three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides.pdf Acesso restrito! | 575,41 kB | Adobe PDF | Ver/Abrir |