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https://hdl.handle.net/1822/31888
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Campo DC | Valor | Idioma |
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dc.contributor.author | Pinho, Eva | por |
dc.contributor.author | Ferreira, Isabel C. F. R. | por |
dc.contributor.author | Barros, Lillian | por |
dc.contributor.author | Carvalho, Ana Maria | por |
dc.contributor.author | Soares, Graça M. B. | por |
dc.contributor.author | Henriques, Mariana | por |
dc.date.accessioned | 2014-12-11T18:10:54Z | - |
dc.date.available | 2014-12-11T18:10:54Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Pinho, Eva; Ferreira, I.C.F.R.; Barros, L.; Carvalho, A.M.; Soares, G.M.B.; Henriques, M. Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds BioMed Research International 2014(814590) 1-8, 2014. | por |
dc.identifier.issn | 2314-6133 | por |
dc.identifier.uri | https://hdl.handle.net/1822/31888 | - |
dc.description.abstract | The present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds. | por |
dc.description.sponsorship | The authors thank the Foundation for Science and Technology (Portugal) for financial support by the E. Pinho grant (SFRH/BD/62665/2009) and L. Barros grant (SFRH/BPD/4609/2000), and by the projects PEst-OE/EQB/LA0023/2013, PEst-C/CTM/UI0264/2011, and PEst-OE/EQB/LA0023/2013. Also, the authors acknowledge the financial support from FEDER through Programa Operacional Factores de Competitividade-COMPETE and to COMPETE/QREN/EU (CIMO strategic project 19 PEst-OE/AGR/UI0690/2011), and through the Project "BioHealth-Biotechnology and Bioengineering approaches to improve health quality", Ref. NORTE-07-0124-FEDER-000027, co-funded by the Programa Operacional Regional do Norte (ON.2-O Novo Norte), QREN, FEDER. The authors also acknowledge the project "Consolidating Research Expertise and Resources on Cellular and Molecular Biotechnology at CEB/IBB", Ref. FCOMP-01-0124-FEDER-027462. | por |
dc.language.iso | eng | por |
dc.publisher | Hindawi Publishing Corporation | por |
dc.rights | openAccess | por |
dc.title | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.hindawi.com/journals/bmri/ | por |
dc.comments | CEB17704 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 8 | por |
oaire.citationIssue | 814590 | por |
oaire.citationTitle | BioMed Research International | por |
oaire.citationVolume | 2014 | por |
dc.date.updated | 2014-11-28T17:56:29Z | - |
dc.identifier.eissn | 2314-6141 | - |
dc.identifier.doi | 10.1155/2014/814590 | por |
dc.identifier.pmid | 24804249 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biomed Research International | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_17704_1.pdf | 428,66 kB | Adobe PDF | Ver/Abrir |