Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/30164
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Silva, Simone Santos | por |
dc.contributor.author | Oliveira, Mariana B. | por |
dc.contributor.author | Mano, J. F. | por |
dc.contributor.author | Reis, R. L. | por |
dc.date.accessioned | 2014-09-17T15:57:57Z | - |
dc.date.available | 2014-09-17T15:57:57Z | - |
dc.date.issued | 2014-05 | - |
dc.date.submitted | 2014-06 | - |
dc.identifier.citation | Silva S. S., Oliveira M. B., Mano J. F., Reis R. L. Bio-inspired aloe vera sponges for biomedical applications, Carbohydrate Polymers, Vol. 112, pp. 264-270, doi:10.1016/j.carbpol.2014.05.042, 2014 | por |
dc.identifier.issn | 0144-8617 | por |
dc.identifier.uri | https://hdl.handle.net/1822/30164 | - |
dc.description.abstract | Chemical composition and biological properties of Aloe vera (AV), a tropical plant, explain its potential use for cosmetic, nutritional and biomedical applications. AV gel present in AV leaves is rich in several compounds, nutrients and polysaccharides. This work proposes using AV gel complex structure and chemical composition, associated with freeze-drying, to produce sponges. To increase the structures stability in aqueous media, a thin coating of gellan gum (GG), was applied onto AV gel. AV-based sponges showed a heterogeneous porous formation, interconnected pores and good porosity(72-77%). The coating with a GG layer onto AV influenced the stability, swelling behavior and mechanical properties of the resulting sponges. Moreover, sponges provided the sustained release of BSA-FTIC, used as a model protein,over 3 weeks. Also, in vitro cell culture studies evidenced that sponges are not cytotoxic for a mouse fibroblast-like cell line. Therefore, developed AV-based sponges have potential use in biomedical applications. | por |
dc.description.sponsorship | The authors acknowledge financial support from Portuguese Foundation for Science and Technology - FCT (Grant SFRH/BPD/45307/2008 and SFRH/BD/64601/2009), "Fundo Social Europeu"- FSE, and "Programa Diferencial de Potencial Humano-POPH". This work was partially supported by European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no. KBBE-2010-266033 (project SPECIAL). | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.rights | restrictedAccess | por |
dc.subject | Aloe vera gel | por |
dc.subject | Gellan Gum | por |
dc.subject | Regenerative medicine | por |
dc.subject | Sponges | por |
dc.title | Bio-inspired Aloe vera sponges for biomedical applications | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0144861714005128 | por |
dc.comments | http://www.3bs.uminho.pt/node/18004 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 264 | por |
oaire.citationEndPage | 270 | por |
oaire.citationTitle | Carbohydrate Polymers | por |
oaire.citationVolume | 112 | por |
dc.date.updated | 2014-09-12T08:38:58Z | - |
dc.identifier.doi | 10.1016/j.carbpol.2014.05.042 | por |
dc.identifier.pmid | 25129743 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Carbohydrate Polymers | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
18004-carbohydrate polymers_ Silva, Reis et al.pdf Acesso restrito! | 1,52 MB | Adobe PDF | Ver/Abrir |