Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/22728
Título: | Cell behaviour in new poly(l-lactic acid) films with crystallinity gradients |
Autor(es): | Bernardo, Vasco Luz, Gisela Alves, N. M. Mano, J. F. |
Palavras-chave: | PLLA Crystallinity kinetics Morphology Biomaterials Biodegradable Cell adhesion |
Data: | 15-Nov-2012 |
Editora: | Elsevier 1 |
Revista: | Materials Letters |
Resumo(s): | We report a new facile method for the development of crystallinity gradients in poly(l-lactic acid) films, based on the gradual dipping of amorphous PLLA samples in a hot bath. Isothermal cold crystallization studies were performed using DSC and optical microscopy in order to find adequate conditions to generate crystallinity gradients in the PLLA films. Cellular response along PLLA samples with graded spherulitic developments was tested: cell adhesion is higher in more crystalline zones due to highly flattened appearance of the cells in regions densely populated with spherulites, but cell density was found to be higher in the more amorphous side. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/22728 |
DOI: | 10.1016/j.matlet.2012.07.088 |
ISSN: | 0167-577X |
Versão da editora: | http://dx.doi.org/10.1016/j.matlet.2012.07.088 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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MaterLetters87_105_12.pdf | 659,41 kB | Adobe PDF | Ver/Abrir |