Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/22423
Título: | Highly diastereoselective synthesis of aza-diels-alder reaction of danishefsky diene wiht glyoxylate imines |
Autor(es): | Goth, Albertino João Brito Alves, M. José Rodríguez-Borges, José E. |
Data: | 2012 |
Editora: | Sociedade Portuguesa de Química (SPQ) |
Resumo(s): | Aza-Diels-Alder reaction is an exceptionally powerful synthetic method for the construction of six-membered nitrogen-heterocycles.[1-3] The reaction of Danishefsky's diene 1 with iminoacetates 2 (imines of glyoxylates) provides a convenient protocol for the synthesis of pipiridone adducts 3 (Scheme 1). In this context, we have performed the synthesis of various cycloadducts, precursors of a wide variety of chiral piperidines with potential use as non-natural amino acids or as precursors of biologically active compounds, including iminosugars (glycomimetics). |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/22423 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDQuim - Comunicações e Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Albertino_6SPJOCS_EB.pdf | Resumo | 102,99 kB | Adobe PDF | Ver/Abrir |