Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/22319
Título: | Synthesis of novel Glycoconjugates derived from Alkynyl heterocycles through a click approach |
Autor(es): | Silva, Marília E. Gonçalves, João Carlos Oliveira Campos, Ana M. F. Oliveira Rodrigues, Lígia M. Esteves, Ana Paula |
Palavras-chave: | 1,2,3-Triazoles Click chemistry Azido sugars Alkynyl heterocycles 3-triazoles 1 2 |
Data: | Jan-2013 |
Editora: | Taylor and Francis |
Revista: | Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry |
Resumo(s): | The synthesis of a series of novel 1,4-disubstituted 1,2,3-triazole compounds bearing a D-glucose derivative and an heteroaromatic system is described. Alkylation of isatin, 3-methyl-carbazole and one tetrahydro-gamma-carboline with propargyl bromide gave their N-propargyl derivatives in good yields. These compounds further reacted with acetylated D-glucose with the azide group in position 1, to give three final products and with peracetylated 6-azido-6-deoxy-alpha-D-methylglucoside giving the corresponding derivative of tetrahydro-gamma-carboline. |
Tipo: | Artigo |
Descrição: | Accepted author version posted online: 05 Jun 2012 |
URI: | https://hdl.handle.net/1822/22319 |
DOI: | 10.1080/00397911.2011.637655 |
ISSN: | 0039-7911 |
e-ISSN: | 1532-2432 |
Versão da editora: | http://dx.doi.org/10.1080/00397911.2011.637655 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Manuscript_SynthComm.pdf | Documento principal | 137,85 kB | Adobe PDF | Ver/Abrir |