Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/21989
Título: | Solvent-free microwave synthesis of 2-, 5- and 9-substituted benzo[a]phenoxazinium chlorides |
Autor(es): | Firmino, A. D. G. Gonçalves, M. Sameiro T. |
Palavras-chave: | Benzo[a]phenoxazines Microwave |
Data: | Mai-2012 |
Resumo(s): | Benzo[a]phenoxazinium salts are usually synthesised by condensation reaction of nitrosoanilines or nitrosonaphthylamines with 1-naphthylamines, 3-aminophenols or 2-napthol. In the last case, monoaminosubstituted benzo[a]phenoxazinium salts should be transformed into the diaminosubstituted derivatives by reaction with amines in the presence of an oxidation agent. The use of a strong mineral acid, such as perchloric or hydrochloric acids, in N,N-dimethylformamide, methanol or ethanol as a solvent, under reflux conditions, is frequently reported for the cyclisation [1-6]. As a continuation of our previous research [3-6], the present work describes for the first time the efficient synthesis of benzo[a]phenoxazinium chloride 1 by condensation reactions of nitrosofenol 2 and 5-aminonaphthalen-2-ol or its derivatives 3 under microwave irradiation in solvent-free conditions or using N,N-dimethylformide, in comparison to conventional heating conditions. These new compounds possess a combination of substituents at the tetracyclic ring that includes the hydroxyl, aminopropoxyl, as well as amine groups, and monoalkylated amines. |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/21989 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CDQuim - Comunicações e Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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abstract_highlights_3PYCheM -ADF1_22-02-2012.pdf Acesso restrito! | Final draft post-refereeing | 156,84 kB | Adobe PDF | Ver/Abrir |