Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/14327
Título: | A study of the short and long-term regulation of E. coli metabolic pathways |
Autor(es): | Lourenço, Anália Carneiro, S. Pinto, José P. Rocha, Miguel Ferreira, Eugénio C. Rocha, I. |
Data: | 2011 |
Editora: | Walter de Gruyter GmbH |
Revista: | Journal of Integrative Bioinformatics |
Resumo(s): | The present study addresses the regulatory network of Escherichia coli and offers a global view of the short- and long-term regulation of its metabolic pathways. The regulatory mechanisms responsible for key metabolic activities and the structure behind such mechanisms are detailed. Most metabolic functions are dependent on the activity of transcriptional regulators over gene expression - the so-called long-term regulation. However, enzymatic regulation - the so-called short-term regulation - often overlays transcriptional regulation and even, in particular metabolic pathways, enzymatic regulation may prevail. As such, understanding the balance between these two types of regulation is necessary to be able to predict and control cell responses, specifically cell responses to the various environmental stresses. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/14327 |
DOI: | 10.2390/biecoll-jib-2011-183 |
ISSN: | 1613-4516 |
Versão da editora: | journal.imbio.de/articles/pdf/jib-183.pdf |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series DI/CCTC - Artigos (papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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jib-183.pdf | Documento principal | 1,97 MB | Adobe PDF | Ver/Abrir |