Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/13093
Título: | Phototriggering of neuroactive amino acids from 5,6-benzocoumarinyl conjugates |
Autor(es): | Fernandes, Maria José G. Costa, Susana P. G. Gonçalves, M. Sameiro T. |
Palavras-chave: | Phototriggers Benzocoumarins Photolysis Neuroactive amino acids Photolabile protecting groups |
Data: | Abr-2011 |
Editora: | Elsevier 1 |
Revista: | Tetrahedron |
Resumo(s): | Uncaging of several neuroactive amino acids, namely β-alanine, tyrosine, 3,4-dihydroxyphenylalanine (DOPA) and glutamic acid from the corresponding 5,6-benzocoumarinyl conjugates was carried out by irradiation at different wavelengths and in different solvent systems. The release of the various amino acids was faster in ACN/HEPES buffer mixtures and for the tyrosine conjugate, an increase in the photolysis reaction rates and the quantitative uncaging of the amino acid was associated with increasing water content in the solvent mixture. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/13093 |
DOI: | 10.1016/j.tet.2011.01.090 |
ISSN: | 0040-4020 |
Versão da editora: | http://www.sciencedirect.com/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Tetrahedron 2011 -1.pdf | Final draft post-refereeing | 334,82 kB | Adobe PDF | Ver/Abrir |